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Southern Medical Journal, 2002
The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinical characteristics of patients with FMF.A total of 96 patients with FMF were evaluated either retrospectively (for those diagnosed before 1997) or
Ali Riza, Odabas +3 more
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The pathogenesis of familial Mediterranean fever (FMF) is unknown, and since no specific laboratory test is yet available, the diagnosis of FMF remains clinical. The purpose of this study was to review clinical characteristics of patients with FMF.A total of 96 patients with FMF were evaluated either retrospectively (for those diagnosed before 1997) or
Ali Riza, Odabas +3 more
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Update in familial Mediterranean fever
Current Opinion in Rheumatology, 2021Purpose of review Familial Mediterranean fever (FMF) is the prototypic autoinflammatory disease. Although the gene associated with the disease was identified 24 years ago, we still have to learn about the pathogenesis of its inflammation and the variation in the phenotype. In this review, we discuss some recent findings in FMF,
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Pediatric Nephrology, 2003
Familial Mediterranean fever (FMF) is the most frequent periodic syndrome characterized by recurrent attacks of polyserositis. Fever, abdominal pain, chest pain, and arthritis/arthralgia are the leading symptoms. It is an autosomal recessive disorder, which primarily affects Jewish, Armenian, Turkish, and Arab populations.
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Familial Mediterranean fever (FMF) is the most frequent periodic syndrome characterized by recurrent attacks of polyserositis. Fever, abdominal pain, chest pain, and arthritis/arthralgia are the leading symptoms. It is an autosomal recessive disorder, which primarily affects Jewish, Armenian, Turkish, and Arab populations.
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The Lancet, 1996
Familial Mediterranean fever is an inherited disorder which causes episodes of severe pain and fever lasting a few days and then recurring shortly afterward. Joints, peritoneal and pleural spaces are primarily affected displaying acute inflammation and an influx of neutrophils into the inflamed area. Keywords: colchicine; amyloid; complement;
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Familial Mediterranean fever is an inherited disorder which causes episodes of severe pain and fever lasting a few days and then recurring shortly afterward. Joints, peritoneal and pleural spaces are primarily affected displaying acute inflammation and an influx of neutrophils into the inflamed area. Keywords: colchicine; amyloid; complement;
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Rheumatology International, 2005
Familial Mediterranean fever (FMF) is the most frequent hereditary inflammatory disease characterized by self-limited recurrent attacks of fever and serositis. It is transmitted in an autosomal recessive pattern and affects certain ethnic groups mainly Jews, Turks, Arabs, and Armenians. FMF is caused by mutations in MEFV gene, which encodes pyrin. This
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Familial Mediterranean fever (FMF) is the most frequent hereditary inflammatory disease characterized by self-limited recurrent attacks of fever and serositis. It is transmitted in an autosomal recessive pattern and affects certain ethnic groups mainly Jews, Turks, Arabs, and Armenians. FMF is caused by mutations in MEFV gene, which encodes pyrin. This
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Familial Mediterranean Fever Gene
New England Journal of Medicine, 1998To the Editor: Babior and Matzner (Nov. 20 issue)1 state that the recently identified familial Mediterranean fever (FMF) gene2,3 can be used to establish the diagnosis of this disease.
A H, Holmes, D R, Booth, P N, Hawkins
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Familial Mediterranean fever in Arabs
The Lancet, 2006Autoinflammatory diseases are a group of disorders characterised by seemingly unprovoked inflammation in the absence of high-titre autoantibodies or antigen-specific T cells, and include the hereditary periodic fever syndromes. Familial Mediterranean fever (FMF) is an archetypal autoinflammatory disorder, which is autosomal recessive and has a high ...
Hatem, El-Shanti +2 more
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Familial Mediterranean fever and microRNAs
International Journal of Immunogenetics, 2023AbstractFamilial Mediterranean fever (FMF) is an inherited disorder caused by the gain of function mutations in MEFV (MEditerranean FeVer) gene loci. FMF affects more than 100,000 people worldwide and generally seen in the eastern Mediterranean region and causes the lifelong diseases which have a significant effect on the patient's life quality and ...
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The arthritis of familial mediterranean fever
Seminars in Arthritis and Rheumatism, 1992Familial Mediterranean fever (FMF) is a disease of unknown etiology and pathogenesis. In addition to fever, arthritis is among its most frequent manifestations. The arthritis of FMF is typically an acute, episodic, self-limited process with no sequelae.
A, Garcia-Gonzalez, M H, Weisman
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Pericarditis in Familial Mediterranean Fever
Archives of Pediatrics & Adolescent Medicine, 1968FAMILIAL Mediterranean fever (FMF) is an autosomal recessive disorder prevalent among Sephardi Jews, Armenians, and Levantine Arabs. It is characterized by (1) recurrent episodic attacks of fever accompanied by pain in the abdomen, chest, or joints, and (2) early death due to amyloidosis.
U, Raviv, A, Rubinstein, A E, Schonfeld
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