Genetic and Epigenetic Regulation of MEFV Gene and Their Impact on Clinical Outcome in Auto-Inflammatory Familial Mediterranean Fever Patients [PDF]
Current Issues in Molecular Biology, 2023 Epigenetic modifications play a pivotal role in autoimmune/inflammatory disorders and could establish a bridge between personalized medicine and disease epidemiological contexts.
May E. Zekry +5 more
doaj +4 more sources
Evaluation of the Clinical Effects and Frequency of MEFV Gene Mutation in Patients with Inflammatory Bowel Disease [PDF]
Gastroenterology Research and Practice, 2021 Background. The clinical and pathological features of inflammatory bowel disease (IBD) and Familial Mediterranean Fever (FMF) are similar. Objective. Here, the frequency of Mediterranean Fever (MEFV) gene mutation and its effect on the outcome of IBD ...
S. Sahin, D. Gulec, S. Günay, C. Cekic
doaj +2 more sources
Recurrent synovitis of hip and MEFV gene related arthritis in children [PDF]
Pediatric Rheumatology Online Journal, 2020 Background Recurrent and relapsing arthritis has been proposed to describe a group of arthritis with recurring and periodic nature, in which the joints are intermittently involved.
Farhad Salehzadeh, Mehrdad Mirzarahimi
doaj +2 more sources
MEFV gene mutations in neuro‐Behçet's disease and neuro‐Sweet disease [PDF]
Annals of Clinical and Translational Neurology, 2019 Mediterranean fever (MEFV) gene mutations are associated with familial Mediterranean fever (FMF). Recent studies have suggested that MEFV gene mutations may act as disease modifiers in neuro‐Behçet's (NBD) disease and neuro‐Sweet disease (NSD).
Hidehiro Ishikawa +14 more
doaj +2 more sources
Frequencies of the MEFV Gene Mutations in Azerbaijan [PDF]
Balkan Journal of Medical Genetics, 2022 The MEFV (familial Mediterranean fever gene) researches were performed in the population of the Republic of Azerbaijan in 2016–2021. Seven mutations of the MEFV gene were identified in heterozygous, homozygous and compound homozygous conditions: R761H ...
Huseynova LS, Mammadova SN, Aliyeva KAA
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A novel single variant in the MEFV gene causing Mediterranean fever and Behçet’s disease: a case report [PDF]
Journal of Medical Case Reports, 2018 Background Familial Mediterranean fever is an autoinflammatory disease of unknown etiology, characterized clinically by recurrent attacks of sudden-onset fever with arthralgia and/or thoracoabdominal pain and pathogenetically by autosomal recessive ...
Maria Zerkaoui +4 more
doaj +2 more sources
Associations of MEFV gene variants, IL-33, and sST2 with the risk of Henoch-Schönlein purpura in children [PDF]
HeliyonObjective: Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children. HSP is a multifactorial inflammatory disease, but its pathogenesis is still unclear.
Yang Ruan, Longlong Xie
doaj +2 more sources
The clinical significance of the Mediterranean fever gene MEFV variants in Castleman disease [PDF]
Communications MedicineBackground Idiopathic Multicentric Castleman Disease, Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Organomegaly (iMCD-TAFRO) is a rare cytokine storm syndrome with high mortality.
Yumo Du +18 more
doaj +2 more sources
Immunogenic Potential of the Mediterranean Fever Gene in Patients with Coronavirus Disease: A Cross-Sectional Study [PDF]
Iranian Journal of Medical Sciences, 2023 Background: In December 2019, an outbreak of pneumonia caused by the novel coronavirus disease 2019 (COVID-19) became a pandemic and caused a global health crisis.
Farhad Salehzadeh +5 more
doaj +1 more source
Improvement of MEFV gene variants classification to aid treatment decision making in familial Mediterranean fever [PDF]
Rheumatology, 2020 Angela Maria D’Uggento +2 more
exaly +2 more sources