Results 11 to 20 of about 6,939 (203)

Genetic Analysis of MEFV Gene Pyrin Domain in Patients With Behçet's Disease [PDF]

Mediators of Inflammation, 2006
Objectives. Behçet's disease (BD) is a systemic vasculitis with recurrent oral and genital ulcers and uveitis. MEFV gene, which is the main factor in familial Mediterranean fever (FMF), is also reported to be a susceptibility gene for BD.
Ahmet Dursun, Hatice Gul Durakbasi-Dursun, Ayse Gul Zamani, Zerrin Gülin Gulbahar, Recep Dursun, Cengiz Yakicier   +5 more
doaj   +7 more sources

Genewise detection of variants in MEFV gene using nanopore sequencing. [PDF]

Front Genet
Familial Mediterranean Fever (FMF) is a genetic disorder with complex inheritance patterns and genotype-phenotype associations, and it is highly prevalent in Armenia. FMF typically follows an autosomal recessive inheritance pattern (OMIM: 249100), though it can occasionally display a rare dominant inheritance pattern with variable penetrance (OMIM ...
Ghukasyan L, Khachatryan G, Sirunyan T, Minasyan A, Hakobyan S, Chavushyan A, Hayrapetyan V, Ghazaryan H, Martirosyan G, Mkrtchyan G, Vardanyan V, Mukuchyan V, Davidyants A, Zakharyan R, Arakelyan A.   +14 more
europepmc   +4 more sources

A novel single variant in the MEFV gene causing Mediterranean fever and Behçet’s disease: a case report [PDF]

Journal of Medical Case Reports, 2018
Background Familial Mediterranean fever is an autoinflammatory disease of unknown etiology, characterized clinically by recurrent attacks of sudden-onset fever with arthralgia and/or thoracoabdominal pain and pathogenetically by autosomal recessive ...
Maria Zerkaoui, Fatima Zahra Laarabi, Yousra Ajhoun, Bouchra Chkirate, Abdelaziz Sefiani   +4 more
doaj   +2 more sources

The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis [PDF]

Pediatric Rheumatology Online Journal, 2020
Background Systemic juvenile idiopathic arthritis (sJIA) has many clinical features overlapping with familial Mediterranean fever (FMF), which is caused by mutations in MEFV gene. And FMF patients were easily misdiagnosed as sJIA in China.
Linqing Zhong, Wei Wang, Ji Li, Mingsheng Ma, Lijuan Gou, Changyan Wang, Zhongxun Yu, Tiannan Zhang, Yanqing Dong, Qijiao Wei, Hongmei Song   +10 more
doaj   +2 more sources

Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever [PDF]

BMC Medical Genetics, 2011
Background MEFV mutations and decreased expression level of the gene are related to FMF pathology. DNA methylation at CpG islands is a well-known mechanism for transcriptional silencing.
Ozdogan Huri, Hatemi Gulen, Celikyapi Erdem Gokce, Arisoy Nil, Kasapcopur Ozgur, Kirectepe Asli K, Tahir Turanli Eda   +6 more
doaj   +3 more sources

Associations of MEFV gene variants, IL-33, and sST2 with the risk of Henoch-Schönlein purpura in children [PDF]

Heliyon
Objective: Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children. HSP is a multifactorial inflammatory disease, but its pathogenesis is still unclear.
Yang Ruan, Longlong Xie
doaj   +2 more sources

The clinical significance of the Mediterranean fever gene MEFV variants in Castleman disease [PDF]

Communications Medicine
Background Idiopathic Multicentric Castleman Disease, Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Organomegaly (iMCD-TAFRO) is a rare cytokine storm syndrome with high mortality.
Yumo Du, Shuangfeng Xie, Zhen Dai, Wenqi Jia, Wenjuan Li, Long Zhang, Guangzhou Du, Haijiao Zhang, Qiao Lin, Meiping Wu, Yiqing Li, Wenjuan Yang, Jie Xiao, Yongxun Zhuansun, Jianguo Li, Wenying Zhang, Shanping Jiang, Danian Nie, Kezhi Huang   +18 more
doaj   +2 more sources

MEFV Gene Profile in Northwest of Iran, Twelve Common MEFV Gene Mutations Analysis in 216 Patients with Familial Mediterranean Fever

Iranian Journal of Medical Sciences, 2015
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease with autosomal recessive inheritance pattern often seen around the Mediterranean Sea. It is characterized by recurrent episodes of fever and polyserositis and rash.
Farhad Salehzadeh, Mehdi Jafari Asl, Saeid Hosseini Asl, Sepideh Jahangiri, Shahram Habibzadeh   +4 more
doaj   +2 more sources

Immunogenic Potential of the Mediterranean Fever Gene in Patients with Coronavirus Disease: A Cross-Sectional Study [PDF]

Iranian Journal of Medical Sciences, 2023
Background: In December 2019, an outbreak of pneumonia caused by the novel coronavirus disease 2019 (COVID-19) became a pandemic and caused a global health crisis.
Farhad Salehzadeh, Farhad Pourfarzi, Rasool Molatefi, Behzad Davarnia, Ehsan Shahbazfar, Farzad Ahmadabadi   +5 more
doaj   +1 more source

Improvement of MEFV gene variants classification to aid treatment decision making in familial Mediterranean fever. [PDF]

Rheumatology (Oxford), 2020
Accetturo M, D'Uggento AM, Portincasa P, Stella A.   +3 more
europepmc   +2 more sources