Results 11 to 20 of about 4,057 (128)

Genetic Analysis of MEFV Gene Pyrin Domain in Patients With Behçet's Disease

Mediators of Inflammation, 2006
Objectives. Behçet's disease (BD) is a systemic vasculitis with recurrent oral and genital ulcers and uveitis. MEFV gene, which is the main factor in familial Mediterranean fever (FMF), is also reported to be a susceptibility gene for BD.
Ahmet Dursun, Hatice Gul Durakbasi-Dursun, Ayse Gul Zamani, Zerrin Gülin Gulbahar, Recep Dursun, Cengiz Yakicier   +5 more
doaj   +2 more sources

Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels. [PDF]

PLoS ONE, 2009
BACKGROUND:Fibromyalgia syndrome (FMS), a common, chronic, widespread musculoskeletal pain disorder found in 2% of the general population and with a preponderance of 85% in females, has both genetic and environmental contributions.
Jinong Feng, Zhifang Zhang, Wenyan Li, Xiaoming Shen, Wenjia Song, Chunmei Yang, Frances Chang, Jeffrey Longmate, Claudia Marek, R Paul St Amand, Theodore G Krontiris, John E Shively, Steve S Sommer   +12 more
doaj   +1 more source

Frequencies of the Common Mefv Gene Mutations in Adiyaman, Southeast Anatolia, Turkey

Balkan Journal of Medical Genetics, 2014
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by fever and serosal inflammation. The reasons for the disorder are mutations in the Mediterranean fever (MEFV) gene; the most common of which are M694V, M680I, M694I and
Korkmaz D. T., Atak P. G., Çelik Ç.
doaj   +1 more source

Atypical Familial Mediterranean Fever in a Japanese Boy with Heterozygous MEFV p.Ser503Cys Exon 5 Variant

Case Reports in Pediatrics, 2021
Periodic fever syndromes are heterogeneous diseases. Familial Mediterranean fever (FMF) is one of the hereditary periodic fever diseases caused by a Mediterranean fever (MEFV) gene abnormality.
Tomonobu Sato, Shunichiro Takezaki, Takeru Goto, Shinichi Ishikawa, Kazumi Oura, Asuka Takahata, Haruki Shiraishi, Yuji Maruo, Norio Sato, Takashi Suganuma, Makoto Mikawa   +10 more
doaj   +1 more source

Existe uma relação entre a artrite gotosa e as mutações genéticas da febre familiar do Mediterrâneo?

Revista Brasileira de Reumatologia, 2015
RESUMOObjetivoA artrite gostosa e a febre familiar do Mediterrâneo (FFM) compartilham algumas características clínicas e patológicas, como ser classificada como uma doença autoimune inflamatória, ter associação com o inflamassoma, manifestar artrite ...
Ismail Sari, Ismail Simsek, Yusuf Tunca, Bunyamin Kisacik, Hakan Erdem, Salih Pay, Hasan Fatih Cay, Davut Gul, Ayhan Dinc   +8 more
doaj   +1 more source

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis. [PDF]

PLoS Genetics, 2019
Ankylosing spondylitis (AS) is a highly heritable immune-mediated arthritis common in Turkish and Iranian populations. Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory disease most common in people of Mediterranean origin ...
Zhixiu Li, Servet Akar, Handan Yarkan, Sau Kuen Lee, Pınar Çetin, Gerçek Can, Gökce Kenar, Fernur Çapa, Omer Nuri Pamuk, Yavuz Pehlivan, Katie Cremin, Erika De Guzman, Jessica Harris, Lawrie Wheeler, Ahmadreza Jamshidi, Mahdi Vojdanian, Elham Farhadi, Nooshin Ahmadzadeh, Zeynep Yüce, Ediz Dalkılıç, Dilek Solmaz, Berrin Akın, Salim Dönmez, İsmail Sarı, Paul J Leo, Tony J Kenna, Fatos Önen, Mahdi Mahmoudi, Matthew A Brown, Nurullah Akkoc   +29 more
doaj   +1 more source

Frequency and Distribution of MEFV Gene Mutation in Familial Mediterranean Fever Patients: A Single Center Experience

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 2021
ObjectiveWe aimed to evaluate frequency and distribution MEFV gene mutation variants in patients with presumptive diagnosis of Familial Mediterranean Fever (FMF).
Şebnem Özemri Sağ, Adem Alemdar, Lamiya Aliyeva, Niyazi Kaya, Şehime G Temel   +4 more
doaj   +1 more source

Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels. [PDF]

PLoS ONE, 2012
Familial Mediterranean Fever (FMF) is an inherited autoinflammatory disorder characterized by unprovoked episodes of fever and inflammation. The associated gene, MEFV (Mediterranean Fever), is expressed primarily by cells of myeloid lineage and encodes ...
Pamela R Hesker, MyTrang Nguyen, Martina Kovarova, Jenny P-Y Ting, Beverly H Koller   +4 more
doaj   +1 more source

The relation of MEFV gene variants to clinical phenotype and selected laboratory markers in Egyptian patients with familial Mediterranean fever

Journal of the Arab Society for Medical Research
Background/aim Familial Mediterranean fever (FMF) is an autoinflammatory disease, with a high prevalence in the Mediterranean region. It is brought out by variants in the MEFV gene.
Hala T. El-Bassyouni, Ghada Nour Eldeen, Mona F. Sokkar, Mohamed B. Taher, Mohammed M. Sayed-Ahmed, Iman I. Salama, Hala M. Raslan   +6 more
doaj   +1 more source

Idiopathic CRMO and MEFV Gene Variant Alleles: Is There Any Relationship?

Case Reports in Rheumatology, 2019
Background and Objective. CRMO is an inflammatory disease of bone that occurs more often in children. The clinical manifestations are intermittent fever, pain, and bone lesions, especially in long bones.
Farhad Salehzadeh, Hassan Anari, Sepehr Sarkhanloo   +2 more
doaj   +1 more source