Results 51 to 60 of about 35,452 (278)

A novel single variant in the MEFV gene causing Mediterranean fever and Behçet’s disease: a case report

Journal of Medical Case Reports, 2018
Background Familial Mediterranean fever is an autoinflammatory disease of unknown etiology, characterized clinically by recurrent attacks of sudden-onset fever with arthralgia and/or thoracoabdominal pain and pathogenetically by autosomal recessive ...
Maria Zerkaoui, Fatima Zahra Laarabi, Yousra Ajhoun, Bouchra Chkirate, Abdelaziz Sefiani   +4 more
doaj   +1 more source

Autoinflammatory diseases: a possible cause of thrombosis? [PDF]

, 2015
Autoinflammatory diseases are a group of disorders due to acquired or hereditary disfunction of innate immune system and characterized by systemic or localized manifestations. The prototype is Familial Mediterranean Fever, a monogenic hereditary disorder,
Francesco Orlandini, Micaela La Regina, Raffaele Manna   +2 more
core   +2 more sources

The Use of Interleukine-1 Inhibitors in Familial Mediterranean Fever Patients: A Narrative Review

Frontiers in Immunology, 2020
Purpose: Familial Mediterranean fever (FMF) is the most common monogenic auto-inflammatory disease characterized by recurrent attacks of fever and serositis.
V. Hentgen, C. Vinit, A. Fayand, S. Georgin-lavialle   +3 more
semanticscholar   +1 more source

Familial Mediterranean fever and asthma

Rheumatology, 2021
Abstract Objective To assess the association between FMF and asthma. Methods This study was designed as a cross-sectional study.
Avishai M Tsur, Abdulla Watad, Omer Gendelman, Daniel Nissan, Arnon D Cohen, Howard Amital   +5 more
openaire   +2 more sources

A patient with familial Mediterranean fever mimicking diarrhea-dominant irritable bowel syndrome who successfully responded to treatment with colchicine: a case report

Journal of Medical Case Reports, 2022
Background Irritable bowel syndrome is a functional gastrointestinal disease. Visceral hypersensitivity is the most important pathophysiology in irritable bowel syndrome. Currently, diagnosis of irritable bowel syndrome is based on symptoms and exclusion
Shima Kumei, Masatomo Ishioh, Yuki Murakami, Katsuyoshi Ando, Tsukasa Nozu, Toshikatsu Okumura   +5 more
doaj   +1 more source

Updates on the role of epigenetics in familial mediterranean fever (FMF)

Orphanet Journal of Rare Diseases
Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutations in the MEFV ( ME diterranean F e V er) gene that affects people originating from the Mediterranean Sea.
Ahlam Chaaban, Zeina Salman, Louna Karam, P. H. Kobeissy, José-Noel Ibrahim   +4 more
semanticscholar   +1 more source

Familial Mediterranean fever without cardinal symptoms and role of genetic screening

Reumatismo, 2012
Familial mediterranean fever is an autosomal recessive disorder characterized by paroxysmal episodes of fever and serosal inflammation. The classical presentation is fever and severe recurrent abdominal pain due to serositis that lasts for one to three ...
I. Hacıbekiroglu, M.S. Dal, C. Bes, H. Buyukhatipoglu, T. Ulas, H.G. Apucu, F. Borlu   +6 more
doaj   +1 more source

Experimental models in Familial Mediterranean Fever (FMF): Insights into pathophysiology and therapeutic strategies.

Experimental and molecular pathology (Print)
Familial Mediterranean Fever (FMF) is a recurrent polyserositis characterized by self-limiting episodes or attacks of fever along with serosal inflammation. It mainly impacts people of the Mediterranean and Middle Eastern basin.
N. Mezher, Ola Mroueh, Louna Karam, José-Noel Ibrahim, P. H. Kobeissy   +4 more
semanticscholar   +1 more source

The Efficacy, Safety and Tolerability of Canakinumab in the Treatment of Familial Mediterranean Fever: A Systematic Review of the Literature

Journal of Inflammation Research, 2020
Familial Mediterranean Fever (FMF) is the most prevalent genetic autoinflammatory disorder. In most patients, treatment with colchicine can prevent attacks of fever and inflammation.
M. Kačar, S. Savic, J. V. D. van der Hilst   +2 more
semanticscholar   +1 more source

EULAR recommendations for the management of familial Mediterranean fever

Annals of the Rheumatic Diseases, 2016
Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, but many rheumatologists are not well acquainted with its management.
S. Ozen, E. Demirkaya, B. Erer, A. Livneh, E. Ben-Chetrit, G. Giancane, H. Ozdogan, I. Abu, M. Gattorno, P. Hawkins, Sezin Yuce, T. Kallinich, Y. Bilginer, D. Kastner, L. Carmona   +14 more
semanticscholar   +1 more source