Results 61 to 70 of about 165,409 (268)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Speaker recognition based on auditory impression: The role of familiarity with the speaker and language [PDF]

open access: yesNBP: Nauka, bezbednost, policija
Speech is a fundamental means of interpersonal communication. Speaker identification based on voice and speech can be analysed through two perspectives, expert listening by trained phoneticians, for the purpose of forensic speaker identification, and by ...
Šešum Mia   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Kin recognition in three samples of Phytoseiulus persimilis (Acari: Phytoseiidae)

open access: yesPersian Journal of Acarology, 2013
Kin recognition as an important phenomenon which influences species fitness is mediated by mechanisms such as association or familiarity. Here, we have investigated either prior association or relatedness would affect the predatory mite, Phytoseiulus ...
Abolfazl Zeraatkar   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Being-with: A study of familiarity [PDF]

open access: yesInteracting with Computers, 2008
How people learn to use an interactive device has always been an important field of research in human-computer interaction (HCI). The theoretical bases of which have ranged from the traditional cognitive perspectives through situated learning to collectivist - social perspectives.
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Empresas familiares: a sucessão familiar

open access: yes, 2023
Esta investigação estudou de forma abrangente e detalhada o processo de sucessão familiar em empresas familiares, destacando a sua importância para a sustentabilidade e crescimento dessas organizações. Através da revisão da literatura e da análise de estudos de caso envolvendo uma empresa de material elétrico, que irá ocorrer uma a sucessão, e uma ...
openaire   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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