Results 111 to 120 of about 71,567 (304)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Livskvalitet i familier

open access: yesSociologisk Forskning, 2007
Kjersti Melberg
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

O ensino do léxico: As expressões idiomáticas

open access: yesTrabalhos em Linguística Aplicada, 2012
Cet article a l'intention de contribuer à l'enseignement d'un secteur très spécial du lexique, étant donné sa haute fréquence dans l'usage familier de n'importe quelle langue.
Cláudia Maria Xatara
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Regard sur une forme langagière ivoirienne à partir de la structure"n'a qu'à+infinitif": valeur restrictive ou valeur modale?

open access: yesEstudios Románicos, 2013
La norme grammaticale emploie la locution adverbiale «ne…que» pour res-treindre le sens d’un verbe à son élément complétif. L’usage de la forme restrictive relève du langage soutenu.
Koffi Paul Konan
doaj  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

La réalité sociale : structure et qualité.

open access: yesEspacesTemps.net, 2010
Les deux philosophes Pierre Livet et Frédéric Nef, le premier proche et familier de la sociologie pragmatique, le second célèbre pour son œuvre de métaphysicien, élaborent dans cet ouvrage une ontologie de la réalité sociale, qu’ils présentent sous l ...
Nina Schmidt
doaj  

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