Results 141 to 150 of about 27,020,150 (302)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

An Innovative Approach to Delivering a Family-Based Intervention to Address Parental Alcohol Misuse: Qualitative Findings from a Pilot Project. [PDF]

Int J Environ Res Public Health, 2022
Alderson H, Mayrhofer A, Smart D, Muir C, McGovern R.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Neuroplasticity associated with changes in conversational turn-taking following a family-based intervention. [PDF]

Dev Cogn Neurosci, 2021
Romeo RR, Leonard JA, Grotzinger HM, Robinson ST, Takada ME, Mackey AP, Scherer E, Rowe ML, West MR, Gabrieli JDE.   +9 more
europepmc   +1 more source

An evaluation of ‘Families for Health’ : a new family-based intervention for the management of childhood obesity [PDF]

Objectives - To develop and pilot a community-based family programme, ‘Families for Health’, for intervention with overweight and obese children aged 7-11 years.
Robertson, Wendy
core  

The person-based approach to intervention development: application to digital health-related behavior change interventions

, 2015
This paper describes an approach that we have evolved for developing successful digital interventions to help people manage their health or illness. We refer to this as the “person-based” approach to highlight the focus on understanding and accommodating
Yardley, Lucy, Muller, Ingrid, Bradbury, Katherine, Morrison, Leanne   +3 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Efficacy of a Family-Based Intervention for HIV Prevention with Hispanic Adolescents with Same Gender Sexual Behaviors. [PDF]

Prev Sci, 2022
Ocasio MA, Lozano A, Lee TK, Feaster DJ, Carrico A, Prado G.   +5 more
europepmc   +1 more source

Family burden and social network in schizophrenia vs. physical diseases: preliminary results from an Italian national study

, 2006
OBJECTIVE: To compare burden and social network in families of patients with schizophrenia or physical diseases. METHOD: A total of 709 relatives of patients with schizophrenia and 646 relatives of patients with physical diseases were recruited in 169 ...
C. De Rosa, L. Magliano, M. Maj, MAGLIANO, Lorenza, MAJ, Mario, A. Fiorillo, FAMILY INTERVENTION WORKING GROUP, FIORILLO, Andrea, DE ROSA C   +8 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source