Results 111 to 120 of about 2,547,941 (344)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Neuroticism, work demands, work-family conflict and job stress consequences

open access: yesMedycyna Pracy, 2014
Background: The objective of the study was to the determine of neuroticism, requirements of the labor market and work-family conflict while exploring consequences of various aspects of job stress in occupationally active parents.
Bogusława Halina Lachowska
doaj   +1 more source

Direct and indirect effects of work-family conflict on job performance [PDF]

open access: yes, 2008
A model is developed on the effects of work-family conflict on employees’ emotional exhaustion, job satisfaction and job performance based on the role theory and the conservation of resources theory as well as related studies.
Ahmad, Aminah
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Relationship Between Work-Family Conflict and Perceived Organizational Support Among Nurses of Kurdistan University of Medical Sciences

open access: yesCaspian Journal of Health Research, 2021
Background: Due to the importance of work-family conflict, it is necessary to find its relationship with organizational variables like perceived organizational support.
Boshra Ebrahimi   +3 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Qualitative study of work-family conflict in managerial couples, A. Are we overlooking some fundamental questions? [PDF]

open access: yes
In this study I explore the phenomenon of work-family conflict in an "unconventional" way. Most studies on work-family conflict are quantitative studies of individuals, based on Anglo-Saxon samples.
Poelmans, Steven
core  

Work family conflict among public school principals [PDF]

open access: yes, 2016
Being a school principal is not an easy job. There never seems to be enough time to devote to everything and everyone that need attention. The days are often long and mentally exhausting. Research suggests that for principals, finding a healthy balance
Roush, Candace S.
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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