Results 141 to 150 of about 2,547,941 (344)

Associations of Work-Family Conflict, Job Satisfaction, Family Satisfaction and Life Satisfaction: A Study of Married Female Secretaries [PDF]

open access: yes, 1996
This study examined the consequences of work-family conflict through path analytic associations of work family conflict, job satisfaction, family satisfaction and life satisfaction. Data were obtained from 120 married female secretaries in the state of
Ahmad, Aminah
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Analisis Pengaruh Work Family Conflict dan Role Stress terhadap Komitmen Organisasional Karyawan [PDF]

open access: yes, 2016
Jumlah villa di Bali yang semakin berkembang, menuntut The Clubs Villas memiliki keunggulan kompetitif dalam bersaing dengan memperhatikan karyawan, melalui kejadian masalah-masalah dalam pengelolaan sumber daya manusia khususnya dalam membina komitmen ...
Sudibya, G. A. (Gede)   +1 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Role conflict, work-family conflict and job satisfaction among single mother employees. [PDF]

open access: yes, 2009
Despite previous studies on job satisfaction and its antecedents, few studies have explored the interrelationships between role conflict, work-family conflict and job satisfaction.
Ahmad, Aminah, Ngah, Noryati
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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