Results 221 to 230 of about 16,465,093 (249)

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Epigenetic regulators are preferentially coordinated with protocadherin gene expression across the human brain: a genome-wide co-expression analysis. [PDF]

Front Genet
Harbert DH.
europepmc   +1 more source

A Novel Technique for Validating Copy Number Variants and Its Application in Familial Exudative Vitreoretinopathy. [PDF]

Hum Mutat
Zhang LL, Zhao ZJ, Chen KX, Ju YQ, Gao FJ, Zong Y, Chang Q, Huang X, Zhang T, Xu GZ.   +9 more
europepmc   +1 more source

Time-course transcriptome and WGCNA reveal tissue-specific genes in 'White BK-1' rye during early cold acclimation stage. [PDF]

Front Plant Sci
Wang D, Ren W, Wang X.
europepmc   +1 more source

Integrated analysis of chromatin accessibility and transcriptome profiles in granulosa cells of sheep with different FecB genotypes. [PDF]

BMC Genomics
Liu Q, Hou S, Liu K, Chi R, Pu X, Xiang Y, Gu S, Liu Y, Chu M.   +8 more
europepmc   +1 more source

Stag2-dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome.

Blood
Sudunagunta VS, Stewart EM, Chen Y, Yan H, Fernando S, Scoca V, Pantazi J, Deng R, Xu JJ, Mohandas N, Viny AD.   +10 more
europepmc   +1 more source

Work Support and Family Support as Predictors of Work-to-family Enrichment and Family-to-work Enrichment

Global Business Review, 2017
Of late, the relationship between work–family enrichment and support has started gaining some attention within the organizational behaviour literature. However, support emerging from the family front has often been neglected in previous studies.
Sarika Jain, Shreekumar K Nair
exaly   +2 more sources