Results 121 to 130 of about 8,507,446 (351)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Enfances, Familles, Générations, 2018 Research framework : In the Quebec countryside of the latter 19th century, orphaned minors depended closely on what could be gleaned from their family inheritance and these financial rights sometimes led to litigation.Objectives : The author examines ...
Thierry Nootens
doaj
Different coloured tears: Dual cultural identity and Tangihanga – A directed study [PDF]
, 2010 Although whānau/family that are configured by both Pākehā and Māori identities number significantly within New Zealand, there has been little or no attention paid to the ways in which these identities influence the bereavement processes that will ...
Edge, Kiri, Nikora, Linda Waimarie
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Preventive Care in Nursing and Midwifery JournalBackground: The rising prevalence of marital conflict and its detrimental impact on individual and family well-being underscores the urgent need for effective interventions.
Seyedeh Farzaneh Jafari +2 more
doaj +1 more source
Work-family conflict and stress [PDF]
, 2005 Over the past twenty years, increasing attention has been paid by researchers and organizations to the interface between people’s work and their family lives.
Brough, Paula, O’Driscoll, Michael P.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Brazilian Journal of PsychiatryObjective: This study examined the effects of socioeconomic status as a possible moderator of the effects of family conflict on externalizing/internalizing behavior and hippocampal and amygdala volume.
Elizabeth Trejos-Castillo +9 more
doaj +1 more source
Pengaruh Work-Family Conflict Terhadap Komitmen Organisasi: Kepuasan Kerja Sebagai Variabel Mediasi [PDF]
, 2013 Several studies have examined how work-family conflict affectorganizational commitment. The aim of the study was to test whether work-family conflict affect the commitment variable mediated by satisfaction.
Buhali, G. A. (Giovanny) +1 more
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