Results 51 to 60 of about 1,286,722 (262)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The association between demographic and familial characteristics and psychological properties of adolescents

Journal of Research in Medical Sciences, 2019
Background: We aimed to investigate the association between demographic and familial characteristics and psychological properties of adolescents including identity style, spiritual intelligence (SI), perceived parenting style (PPS), family functioning ...
Seyed Badredin Najmi, Silva Hovsepian, Assiyeh Jamshidibeyk, Leila Nasiripour, Mohammad Reza Maracy   +4 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Prospective associations of family conflict with alcohol expectancies in the adolescent brain cognitive development study: effects of race and ethnicity

Frontiers in Psychiatry
IntroductionAlcohol expectancies predict subsequent alcohol use and related problems among adolescents, although predictors of alcohol expectancies remain unclear.
Skye C. Bristol, Micah E. Johnson, Wesley K. Thompson, Matthew Albaugh, Alexandra Potter, Hugh Garavan, Nicholas Allgaier, Masha Y. Ivanova   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Examination of the Relationship between Family and U.S. Latinos’ Physical Health

Field Actions Science Reports, 2010
Latinos, especially immigrant Latinos, have lower mortality rates and some better health outcomes than U.S.-born Latinos and whites, a situation called the Latino Paradox.
Georgiana Bostean
doaj  

Family Conflict and Gun Carrying in Adolescence: Multilevel Analysis of Household and Neighborhood Effects in Los Angeles County

Adolescents
Background: Firearm-related injuries are the leading cause of death among children and adolescents (ages 1 to 19 years) in the United States. Access to and carrying firearms are key risk factors for violence and adolescent firearm use.
Kathryn M. Barker, Devin Gregoire, Naomi Wilcox, Maryam Izadshenas, Anita Raj   +4 more
doaj   +1 more source

The Causal Relationship between Family Cohesion, Family Conflict, and School Satisfaction Mediated by Self-Efficacy among Female Elementary School Students [PDF]

خانواده و پژوهش, 2021
This research was undertaken to investigate the causal relationship between family cohesion, family conflict, and school satisfaction mediated by self-efficacy among female elementary school students. The statistical population of the study was comprised
M. Hojjati, M. Sadeghi, Ph.D., M. Abbasi, Ph.D., A. Senobar   +3 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source