Results 61 to 70 of about 15,064,686 (342)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Social Capital Capacity as Prediction of Dengue Control [PDF]

open access: yes, 2016
The program of elimination of mosquito breeding places is still low since there is no public participation effort in vector control. Social capital is key factor for sustaining any health programs implemented.
Kartono, D. T. (Drajat)   +3 more
core  

A List of the Tenebrionidae of Michigan (Coleoptera) [PDF]

open access: yes, 2017
The family Tenebrionidae, the darkling beetles, containing more than 14,000 species, is found primarily in the tropics and arid regions. As would therefore be expected, Michigan\u27s cool, moist environment is not attractive to very many tenebrionids ...
Spilman, T.J.
core   +3 more sources

Correlation between Family Environment and Suicidal Ideation in University Students in China

open access: yesInternational Journal of Environmental Research and Public Health, 2015
Background: This study investigated the association between suicidal ideation and family environment. The sample included 5183 Chinese university students. A number of studies on suicidal ideation have focused on individuals rather than families.
Hui Zhai   +8 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Mum. Dad. Do you need some help with that? Empowering older Australians in a digital era. [PDF]

open access: yes, 2013
The change to a digital environment for Australian families is more than simply adopting internet connectivity or a mobile phone. Moving from an analog environment and into a digital sphere for many individuals is confronting: the transition requires ...
Scott Rickard
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Roles of Need for Achievement and Family Environment in Stimulating Entrepreneurial Interest through Self-Efficacy

open access: yesJurnal Economia, 2020
: This study was designed to reveal the extent to which the need for achievement and family environment affected entrepreneurial interest through self-efficacy, either directly or indirectly.
Fiarika Dwi Utari, Sukidjo Sukidjo
doaj   +1 more source

Nonsuicidal self-injury and family environment among college students in Kolkata, West Bengal: Mixed method explanatory sequential design

open access: yesJournal of Mental Health and Human Behaviour, 2022
Background: Nonsuicidal self-injury (NSSI) refers to intentional, deliberate, and socially unexpected harming acts to oneself without any intention to die. It is a growing concern among recent mental health professionals.
Arkita Pal, Paramita Roy
doaj   +1 more source

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