Results 81 to 90 of about 15,064,686 (342)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

NGARUH CARA BELAJAR, LINGKUNGAN KELUARGA, DAN FASILITAS BELAJAR TERHADAP PRESTASI BELAJAR EKONOMI AKUNTANSI SISWA KELAS XI IPS SMA NEGERI 4 MAGELANG TAHUN AJARAN 2013/2014

Economic Education Analysis Journal, 2014
Tujuan penelitian ini adalah untuk mengetahui adakah pengaruh positif cara belajar, lingkungan keluarga, dan fasilitas belajar terhadap prestasi belajar ekonomi akuntasi siswa kelas XI IPS SMA Negeri 4 Magelang baik secara simultan maupun parsial ...
Dewi Yonitasari
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Longitudinal study of local authority child and family social workers (wave 1) Findings from a 5 year study of local authority child and family social workers in England. [PDF]

, 2019
The longitudinal study investigates recruitment, retention and career progression in local authority child and family social work over 5 years. This is the first of 5 reports.
Coburn, S, DfE, Felton, J, IFF, Johnson, C, McCaughan, S, McLaughlin, H, Pollock, S, Sanders-Earley, A, Scholar, HF, Winterbotham, M   +10 more
core   +3 more sources

Characterization and measurement of qubit-environment entanglement generation during pure dephasing

, 2015
We consider the coupling of a qubit in a pure state to an environment in an arbitrary state, and characterize the possibility of qubit-environment entanglement generation during the evolution of the joint system, that leads to pure dephasing of the qubit.
Cywiński, Łukasz, Roszak, Katarzyna
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

INCIDENCIA Y FACTORES RELACIONADOS CON EL SÍNDROME CLIMATÉRICO EN UNA POBLACIÓN DE MUJERES MEXICANAS

Revista Chilena de Obstetricia y Ginecología, 2007
Objetivo: Determinar las características del entorno familiar y actitud frente a la menopausia y su influencia en el síndrome climatérico. Métodos: Estudio comparativo en mujeres con menopausia que acudieron como acompañantes a las Unidades de Medicina ...
Genaro Vega M, Adrián Hernández L, Guillermo Leo A, Jesús Vega M, Minerva Escartin Ch, Javier Luengas M, María Guadalupe Guerrero L   +6 more
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Impact of the Family Environment on the Emotional State of Medical Staff During the COVID-19 Outbreak: The Mediating Effect of Self-Efficacy

Frontiers in Psychology, 2020
During the outbreak of the coronavirus disease 2019 (COVID-19), the medical staff was facing severe work pressure, which led to a negative emotional state.
Na Hu, Ying Li, Su-Shuang He, Lei-Lei Wang, Yan-Yan Wei, Lu Yin, Jing-Xu Chen   +6 more
doaj   +1 more source

Decoherence induced by a chaotic environment: A quantum walker with a complex coin

, 2005
We study the differences between the process of decoherence induced by chaotic and regular environments. For this we analyze a family of simple models wich contain both regular and chaotic environments.
A. Nielsen, A. Peres, J. P. Paz, Juan Pablo Paz, Leonardo Ermann, Marcos Saraceno   +5 more
core   +1 more source