Results 31 to 40 of about 3,881,952 (282)

Education in Family Medicine : What has been achieved? [PDF]

, 2012
Contents: Education... historical landmarks - Pierre Mallia; The Malta College of Family Doctors and the Royal College of General Practitioners - John V.
Mallia, Pierre, Malta College of Family Doctors, Agius, Dominic   +2 more
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Women in family farming: An analysis of the Brazilian National Program to strengthen family farming for women

Estudos Sociedade e Agricultura
This study discusses whether the Pronaf Mulher credit, the main public program for family farms in Brazil, has helped increase the participation of women in family farming.
Hilka Pelizza Vier Machado, Marcos Aurélio Brambilla   +1 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Agroecological family farming in Uruguay, innovative and counter-hegemonic contributions to sustainability

Agrociencia Uruguay
Agroecological family farming in Uruguay has a background of over thirty years and is increasingly recognized as a valid option for the transformation of the food system. However, basic and comprehensive information on the sector is not available.
Alberto Gómez Perazzoli, Inés Gazzano, Francisco Dieguez Cameroni   +2 more
doaj   +1 more source

Weed control using natural compounds [PDF]

Pesquisa Agropecuária Brasileira
The objective of this work was to evaluate the weed control efficacy of different plant-derived natural compounds in post-emergence applications. The treatments were alcohol+water (50% v/v), carvacrol (2.5% v/v), eugenol (2.5% v/v), thymol (2.5% v/v ...
Alexandre Magno Brighenti, Alexander Machado Auad, Luís Augusto Calsavara   +2 more
doaj   +2 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

MOTIVASI PETANI DALAM MEMPERTAHANKAN SISTEM TRADISIONAL PADA USAHATANI PADI SAWAH DI DESA PARBAJU JULU KABUPATEN TAPANULI UTARA PROPINSI SUMATERA UTARA

Jurnal Agrisep, 2011
This research aims to identify factors correlated significantly to the motivation of farmers in perseving traditional rainfed farming systems, such as using local seeds and planting once a year.
Reflis Reflis, M. Nurung, Juliana Dewi Pratiwi   +2 more
doaj   +1 more source