Results 41 to 50 of about 60,283 (254)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

MOTIVASI PETANI DALAM MEMPERTAHANKAN SISTEM TRADISIONAL PADA USAHATANI PADI SAWAH DI DESA PARBAJU JULU KABUPATEN TAPANULI UTARA PROPINSI SUMATERA UTARA

open access: yesJurnal Agrisep, 2011
This research aims to identify factors correlated significantly to the motivation of farmers in perseving traditional rainfed farming systems, such as using local seeds and planting once a year.
Reflis Reflis   +2 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

EVALUATING THE ENVIRONMENTAL LICENSING PROCESS OF MARINE CALCAREOUS ALGAE BY THE IBAMA IN BRAZIL: CONTRIBUTIONS TO INSTITUTIONAL LEARNING

open access: yesEnvironmental Smoke
Currently, the efforts of marine research and marine resources exploitation are rising. However, debate usually is divided into economic and conservation approaches.
Luana Sena Ferreira   +1 more
doaj   +1 more source

BESARNYA KONTRIBUSI TENAGA KERJA DALAM KELUARGA TERHADAP PENDAPATAN USAHATANI PADI (Oryza sativa L) SAWAH TADAH HUJAN DI DESA PASAR KAMIS KECAMATAN KERTAK HANYAR KABUPATEN BANJAR PROVINSI KALIMANTAN SELATAN

open access: yesZiraa'ah: Majalah Ilmiah Pertanian, 2018
To the effect this research is subject to be know technically paddy farming management be sighted from technical aspect. Analysing labouring effusing in family and family extern, knowing cost, acceptance and paddy farming income and to know labour ...
Wasdiyanta Wasdiyanta
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Aquisição de alimentos orgânicos pelo Programa Nacional de Alimentação Escolar no Paraná

open access: yesDesenvolvimento e Meio Ambiente, 2022
The present work aims to identify the main obstacles faced and the ways to overcome the acquisition and supply of organic food from family farming by the actors involved in the PNAE in municipalities in the state of Paraná, in addition to pointing out ...
Ana Beatriz Goes Maia Marques   +1 more
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

RESOURCE MANAGEMENT OF FAMILY FARMS [PDF]

open access: yesEkonomika Poljoprivrede (1979), 2007
Porodična gazdinstva suočavaju se sa sve većom konkurencijom na tržištu. Da bi odgovorili zahtevima tržišta gazdinstva moraju na najcelishodniji način koristiti postojeće resurse, povećati produktivnost rada i proizvodni program uskladiti potrebama potrošača.
Rajić, Zoran   +3 more
openaire   +2 more sources

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