Results 61 to 70 of about 605,985 (300)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Corporate Risk in Family Businesses Under Economic Crisis
Innovar: Revista de Ciencias Administrativas y Sociales, 2014 This paper analyses corporate risk in family businesses in conjunction with generalized economic adversity. Using data from Portuguese family-controlled firms for the period of time between 1999 and 2010, we focus on the possibility of asymmetrical ...
Elisabete S. Vieira
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Journal of Financial Management, Markets and Institutions, 2020 In the years following the economic and financial crisis, Italy, where most firms are family-owned, has seen the demise of more companies than any other country.
CARMEN GALLUCCI +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
South African Journal of Business Management, 2011 We compare corporate governance and performance between family and non-family ownership of public listed companies in Malaysia from 1999 through 2005 measured by Tobin’s Q and ROA.
H. Ibrahim, F. A. Samad
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Offshoring to Promote the Internationalization of Family Firms
Journal of Evolutionary Studies in Business, 2017 This paper analyses the impact of sourcing abroad on exporting in the case of Spanish manufacturing firms that are family-owned. Sourcing abroad can be a channel that places the firm in a better position to export, not only because it increases the ...
Fernando Merino
doaj +1 more source
Disclosure quality in family firms listed in the Tehran stock exchange [PDF]
بررسیهای حسابداری و حسابرسی, 2014 This paper studies the disclosure quality in family firms in time period of 2007 to 2012, and aims to answer the question that whether the family factor will affect the disclosure quality.
Kaveh Mehrani1, Akbar Parvaei
doaj +1 more source