Results 91 to 100 of about 1,613,013 (264)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Effects of family functioning and family hardiness on self-efficacy among college students [PDF]

, 2007
Family functioning has been related to numerous developmental problems. Although there are other factors affecting a student?s self-efficacy, this research focused on the effects of family functioning and family hardiness.
Tam, Cai Lian *, Tay, Ee Lin *
core  

Analysis of the Relationship between Emotional Intelligence, Resilience, and Family Functioning in Adolescents’ Sustainable Use of Alcohol and Tobacco [PDF]

, 2019
The use of alcohol and tobacco is related to several variables, which act as risk or protective factors depending on the circumstances. The objectives of this study were to analyze the relationship between emotional intelligence, resilience, and family ...
Barragán Martín, Ana Belén, del Pino Salvador, Rosa María, Gázquez Linares, José Jesús, Molero Jurado, María del Mar, Pérez Fuentes, María Del Carmen   +4 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Association Between Family Functioning and Health-related Quality of Life in Stroke Survivor–Informal Family Caregiver Dyads

Asian Nursing Research
summary: Purpose: Stroke survivors and their informal family caregivers may share the impact of the disease, which may affect family functioning and quality of life (QoL) for both.
Chia-Chi Li, Su-Ju Tsai, Jo-Ching Tai, Tzu-Jung Wu, Shu-Mei Tsai, Shu-Chuan Kao, Hsiang-Chu Pai   +6 more
doaj   +1 more source

Associations between family weight-based teasing, eating pathology, and psychosocial functioning among adolescent military dependents [PDF]

, 2019
Weight-based teasing (WBT) by family members is commonly reported among youth and is associated with eating and mood-related psychopathology. Military dependents may be particularly vulnerable to family WBT and its sequelae due to factors associated with
et al,, Pearlman, Arielle T, Wilfley, Denise E   +2 more
core   +1 more source

Psychometric properties and validation of the Italian version of the Family Assessment Measure Third Edition - Short Version - in a nonclinical sample [PDF]

, 2017
Family functioning plays an important role in developing and maintaining dysfunctional behaviors, especially during adolescence. The lack of indicators of family functioning, as determinants of personal and interpersonal problems, represents an obstacle ...
Giaimo, Flavio, Guariglia, Paola, Parrello, Santa, Pellerone, Monica, Ramaci, Tiziana   +4 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Characterization of family functioning in the alcoholic patient

Acta Médica del Centro, 2014
The family as a primary social group conglomerate is of fundamental importance in society. The problems of family functioning can influence both the onset and decompensation of chronic diseases, in most psychiatric diseases and in health risk behaviors ...
Lourdes M. Jaime Valdés, Luis E. Pérez Guerra, Maritza Rodríguez Díaz, Teresa Vega Díaz, Ismary Díaz Rivas   +4 more
doaj  

Stress and Quality of Life Among Parents of Children with Congenital Heart Disease Referred for Psychological Services [PDF]

, 2018
Objective The study examined parent stress and health‐related quality of life (HRQOL) among families of children with congenital heart disease (CHD) referred for psychological services. Methods Parents of 54 children (85% boys) aged 3 to 13 (Mage = 7.48,
Brosig, Cheryl, Kaugars, Astrida S., Shields, Clarissa   +2 more
core   +1 more source