Results 131 to 140 of about 485,517 (308)

Families of subharmonic functions and separately subharmonic functions

open access: yesComplex Variables and Elliptic Equations, 2019
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openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Family and peer influences on adolescent psychological inflexibility: a regression mixture analysis

open access: yesFrontiers in Psychology
IntroductionAdolescent mental health problems are closely linked to psychological inflexibility. Prior research has identified separate effects of family functioning and peer relationships on psychological inflexibility, but their combined effects ...
Lei Liu   +6 more
doaj   +1 more source

Family functioning variables in nonclinical and "healthy" groups: a comparison of intact families

open access: yes, 1983
The purpose of this research project was three-fold: to assess differences on family functioning scores among a "healthy" sample and a nonclinical group; to explore subscale differences in regard to family communication, family activities, frequency of ...
Denman, Debra Marie
core  

Effects of boundary regulation on children's academic performance: a systems perspective of family functioning

open access: yes, 2005
Systems theory was used to link family functioning in the task of boundary regulation to adolescents' academic performance. Boundary regulation, a family task defined in terms of proximity and generation hierarchy, is believed to be the most critical to ...
Njue, Jane
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Strengthening Aboriginal family functioning: What works and why?

open access: yes, 2008
There is widespread recognition that strong family relationships and good family functioning are essential for individual, family and community wellbeing, as well as providing long-term benefits to broader society.
Roz Walker, Carrington Shepherd
core  

Test of a model of the effects of parental illness on youth and family functioning

open access: yes, 2012
Objective: Parental illness (PI) may have adverse impacts on youth and family functioning. Research in this area has suffered from the absence of a guiding comprehensive framework.
Kenneth I. Pakenham   +4 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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