Results 121 to 130 of about 4,643,088 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Family Functioning, Self-Concept, and Severity of Adolescent Externalizing Problems

, 2006
We investigated direct and shared effects of family functioning and self-concept on the severity of adolescent externalizing problems in a sample of 224 clinically referred adolescents.
Henderson, Craig, Dakof, Gayle, Craig E. Henderson, Howard A. Liddle, Schwartz, Seth, Liddle, Howard, Seth J. Schwartz, Gayle A. Dakof   +7 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Kähler families of Green’s functions

Journal de l’École polytechnique — Mathématiques
In a remarkable series of works, Guo, Phong, Song, and Sturm have obtained key uniform estimates for the Green’s functions associated with certain Kähler metrics. In this note, we broaden the scope of their techniques by removing one of their assumptions and allowing the complex structure to vary.
Guedj, Vincent, Tô, Tat Dat
openaire   +4 more sources

Family functioning, family social support, and life satisfaction among school adolescents in the Federal Land Development Authority (FELDA) area in Johor, Malaysia [PDF]

Adolescents' satisfaction with life can be influenced by various factors, including family environment factors. This study aimed to ascertain the relationship between family functioning and social support on adolescents’ life satisfaction in Johor ...
Azam, Naqi Dahamat, Ma’rof, Aini Azeqa, Jaafar, Siti Nor Jannah, Rosnon, Mohd Roslan   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Intergenerational Transaction of Emotional Health in Collective Family Context: Family Functioning, Parental and Children’s Gratitude, and Their Depression

Background: The current study is intended to examine how positive family functioning, collectively constructed by parents and children in the family context, may contribute to their gratitude and depression, two pivotal human emotions closely related to ...
Jerf W. K. Yeung
core   +1 more source

Loneliness, peer acceptance, and family functioning of Chinese children with learning disabilities: Characteristics and relationships

, 2005
Although children with learning disabilities are often considered to be a heterogeneous group, they are always situated in specific social surroundings such as schools and families with which they interact dynamically in everyday life.
Yan, R, Yu, GL, Y. M. Zhang, Zhang, YM
core   +1 more source

A structural model of psychological vulnerability in the era of social media

Discover Mental Health
Background Psychological vulnerability reflects a heightened susceptibility to psychological distress when individuals encounter stressors, particularly in the absence of adequate coping resources.
Lisfarika Napitupulu, Ateerah Abdul Razak, Didik Widiantoro, Bahril Hidayat, Wahyu Fadilla Perkasa, Syelfi Pasha Nurfadila   +5 more
doaj   +1 more source