Results 81 to 90 of about 2,583,091 (310)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Diagnóstico da tuberculose em pessoas idosas: barreiras de acesso relacionadas aos serviços de saúde
Revista da Escola de Enfermagem da USPEste estudo tem como objetivo analisar as barreiras ao diagnóstico da tuberculose em idosos relacionadas aos serviços de saúde no município de João Pessoa-PB.
Annelissa Andrade Virgínio de Oliveira +5 more
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Frontiers in PsychiatryBackgroundAdopting health-promoting lifestyle (HPL) is crucial for improving overall well-being and reducing the risk of chronic diseases. The relationship between health literacy (HL) and HPL among Chinese community residents is complex, with potential ...
Yunxia Ma +7 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Health Care Equity for Family Medicine Patients and Family Physician Equity [PDF]
, 2022 Marjorie A. Bowman +3 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Coordenação de unidades de saúde da família por enfermeiros: desafios e potencialidades
Revista Gaúcha de EnfermagemTrabalho que parte da reflexão de que, embora a Política Nacional de Atenção Básica não defina o enfermeiro como o coordenador das Unidades de Saúde da Família (USF), muitas vezes este profissional acaba assumindo tal função por diversos fatores que ...
Rafael Cerva Melo, Maria Élida Machado
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Revista Enfermagem UERJ, 2013 Este artigo teve o objetivo de analisar os riscos psicossociais relacionados à carga, ritmo e esquema de trabalho de equipes de saúde da família. O estudo é exploratório, descritivo utilizando-se a abordagem qualitativa dos dados.
Silvia Helena Henriques Camelo +3 more
doaj