Results 161 to 170 of about 12,436,746 (396)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cancer of unknown primary (CUP): does cause of death and family history implicate hidden phenotypically changed primaries? [PDF]

, 2012
Kari Hemminki, Melanie Bevier, Jan Sundquist, Akseli Hemminki   +3 more
openalex   +1 more source

Polycystic Kidney Disease without an Apparent Family History.

Journal of the American Society of Nephrology, 2017
Ioan-Andrei Iliuta, Vinusha Kalatharan, Kairong Wang, E. Cornec-Le Gall, J. Conklin, M. Pourafkari, Ryan R. Ting, Chen Chen, A. Borgo, N. He, Xuewen Song, C. M. Heyer, Sarah R. Senum, Y. Hwang, A. Paterson, P. Harris, K. Khalili, Y. Pei   +17 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Appropriate use of genetics in a young patient with atrioventricular block and family history of sudden cardiac death [PDF]

, 2018
Johnni Rudbeck-Resdal, Jens Cosedis Nielsen, Henning Bundgaard, Henrik Kjærulf Jensen   +3 more
openalex   +1 more source

Southwesterly Town Lot Histories of Fairfield, Pennsylvania

, 2013
Each lot history give the original lot number, original owner, the current address, the owner of the lot in 1860, a description of the lot or dwelling in 1860, a recital of ownership with as much detail as is known, a comprehensive lot history, any known
Smith, Timothy H.
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Availability and Quality of Coronary Heart Disease Family History in Primary Care Medical Records: Implications for Cardiovascular Risk Assessment

, 2014
Paula Dhiman, Joe Kai, Laura Horsfall, Kate Walters, Nadeem Qureshi   +4 more
openalex   +2 more sources

Southeasterly Town Lot Histories of Fairfield, Pennsylvania

, 2013
Each lot history give the original lot number, original owner, the current address, the owner of the lot in 1860, a description of the lot or dwelling in 1860, a recital of ownership with as much detail as is known, a comprehensive lot history, any known
Smith, Timothy H.
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source