Results 161 to 170 of about 1,388,888 (219)

Hereditary Bilateral Retinoblastoma Detected on Screening in a Two-Month-Old Infant With a Strong Family History. [PDF]

Cureus
Bhola DE, Bhola RM, Dindial K.
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Family history of stroke and cardiovascular diseases in early-onset cryptogenic ischaemic stroke. [PDF]

Eur Stroke J
Sihvo MC, Ylikotila P, Zedde M, Pascarella R, Sarkanen T, Jatužis D, Ryliškienė K, von Sarnowski B, Licenik R, Ferdinand P, Kõrv J, Kõrv L, Pezzini A, Fonseca AC, Paula A, Martínez-Sánchez P, Yesilot N, Fromm A, Waje-Andreassen U, Redfors P, Jood K, Huhtakangas J, Sairanen T, Hedman M, Jäkälä P, Ten Cate H, Gerdts E, Lehto M, Sinisalo J, Kittner SJ, Mitchell BD, Lindgren AG, Ilinca A, Putaala J, Tomppo L.   +34 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Moderate-Intensity Aerobic Exercise Induces Ambulatory Hypotension in Young Adults with a Family History of Hypertension. [PDF]

Int J Environ Res Public Health
Queiroz MG, Tobar KDL, Damazo AS, Cambri LT.   +3 more
europepmc   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Family history of premature atherosclerotic cardiovascular disease and lipoprotein(a) levels: a multicohort analysis. [PDF]

Eur J Prev Cardiol
Razavi AC, Bhatia HS, Dardari ZA, Mehta A, Nasir K, Blankstein R, Isiadinso I, Quyyumi AA, Vaccarino V, Fialkow JA, Khoury MJ, Coronado F, Budoff MJ, Blumenthal RS, Whelton SP, Mortensen MB, Sperling LS, Matsushita K, Blaha MJ, Dzaye O.   +19 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Elevating the Role of Family History in ASCVD Prevention: Insights From China-PAR and UK Biobank. [PDF]

JACC Asia
Wu X, Li W.
europepmc   +1 more source