Results 141 to 150 of about 2,265,049 (313)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
How does family medicine clerkship affect the attitudes to family medicine specialization?
Background and Objectives - To investigate whether the attitude of final year medical students to family medicine specialization changes after family medicine clerkship.Method - The authors conducted an analysis of data on 90 final year medical students ...
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
State of family medicine practice in Lebanon
Background: Many difficulties are encountered in family medicine practice and were subject to multinational studies. To date, no study was conducted in Lebanon to assess the challenges that family physicians face.
Abi Rizk, Grace, Helou, Mariana
core +1 more source
The family in family medicine research
J, Froom, M G, Rosen
openaire +3 more sources
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Department of Family Medicine and Community Health, Resident and Fellow Commencement, 2022
Department of Family Medicine and Community Health. (2022). Department of Family Medicine and Community Health, Resident and Fellow Commencement, 2022.
Department of Family Medicine and Community Health
core
The College of Family Physicians of Canada
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Vertebral compression fracture with diffuse idiopathic skeletal hyperostosis
Mayu Uemoto, Junki Mizumoto
doaj +1 more source

