Results 141 to 150 of about 2,265,049 (313)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

How does family medicine clerkship affect the attitudes to family medicine specialization?

open access: yes, 2006
Background and Objectives - To investigate whether the attitude of final year medical students to family medicine specialization changes after family medicine clerkship.Method - The authors conducted an analysis of data on 90 final year medical students ...

core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

State of family medicine practice in Lebanon

open access: yes, 2019
Background: Many difficulties are encountered in family medicine practice and were subject to multinational studies. To date, no study was conducted in Lebanon to assess the challenges that family physicians face.
Abi Rizk, Grace, Helou, Mariana
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Department of Family Medicine and Community Health, Resident and Fellow Commencement, 2022

open access: yes, 2022
Department of Family Medicine and Community Health. (2022). Department of Family Medicine and Community Health, Resident and Fellow Commencement, 2022.
Department of Family Medicine and Community Health
core  

Family Medicine Forum

open access: yesCanadian Medical Education Journal, 2018
The College of Family Physicians of Canada
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Vertebral compression fracture with diffuse idiopathic skeletal hyperostosis

open access: yesJournal of General and Family Medicine, 2022
Mayu Uemoto, Junki Mizumoto
doaj   +1 more source

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