Results 121 to 130 of about 3,214,640 (308)

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Une politique familiale visant une meilleure articulation famille-travail. Enjeux pour des parents québécois de milieu socioéconomique modeste

Enfances, Familles, Générations, 2020
Research Framework: Quebec's family policy, which is very focused on family-work balance, is based in particular on two measures, the Quebec Parental Insurance Plan (QPIP) and the public childcare network.
Annabelle Seery
doaj  

Towards an understanding of bereavement in the pathway to suicide [PDF]

, 2015
Key Points 1. Suicide bereavement is associated with increased depression and risk of suicide. The increasing rate of suicide in Northern Ireland presents a major challenge to health and social care policy. 2.
Galway, Karen, Mallon, Sharon
core  

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Des politiques publiques pour l’Outre-mer renouvelées après la guerre d’Algérie

Études Caribéennes
This article reveals part of the strategy decided upon by the various presidents of the Fifth Republic between 1958 and 1974 to keep France’s overseas departments (DOM) within the French fold: producing knowledge and implementing techniques of social ...
Karine Sitcharn
doaj   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Parenting Beyond Doing: Care, Normativity, and Inequality in Contemporary Family Life

Social Sciences
Parenting research and policy increasingly emphasize visible practices, measurable outcomes, and parental effort as indicators of competence. Across welfare, education, and family intervention contexts, “good parenting” is often evaluated through ...
Vered Ben David
doaj   +1 more source

Family Policy in France: Old Challenges, New Tensions [PDF]

Familienpolitik, Reform, Frankreich, Family policy, Reform ...
Jeanne Fagnani
core  

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

State Trends in Premiums and Deductibles, 2003-2009: How Building on the Affordable Care Act Will Help Stem the Tide of Rising Costs and Eroding Benefits [PDF]

, 2010
Examines 2003-09 state trends in family coverage premiums and deductibles for private employers. Looks at projected savings on premiums if the 2010 healthcare reform succeeds in slowing growth by 1 percentage point annually and weighs policy ...
Cathy Schoen, Kristof Stremikis, Sabrina K. H. How, Sara R. Collins   +3 more
core