Results 131 to 140 of about 3,214,640 (308)
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, EarlyView.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Differences in Family Policies and the Intergenerational Transmission of Divorce [PDF]
The intergenerational transmission of the risk of divorce is a well-known long-term effect of divorce that has been found in many Western societies.
Heike Trappe +2 more
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Raising Expectations: A State Scorecard on Long-Term Services and Supports for Older Adults, People With Physical Disabilities, and Family Caregivers [PDF]
, 2011 Ranks long-term services and supports systems for affordability and access, choice of setting and provider, quality of life and care, and family caregivers support.
Ari Houser +3 more
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Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Demographic Research, 2001 The increasing trend of partnership disruption among families with children in recent decades has been accompanied by substantial changes in traditional gender roles in industrialized countries.
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Mompreneurs, Leaning In and Opting Out: Work/Family Choices under Neo-Liberalism
Atlantis, 2017 This article explores three trends in the search for work-life balance and relates these trends to the neoliberal family policy context in Canada. I argue that these models reflect current ideologies about motherhood, the state, and work.
Shauna Wilton
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Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China
Advanced Science, EarlyView.This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang +3 more
wiley +1 more source
Advanced Science, EarlyView.Inspired by the mimosa, this study develops a flexible triboelectric nanogenerator with a novel microneedle array and battery‐mimetic architecture. The device introduces a spontaneous charge self‐regulation mechanism that confines the electric field below the air breakdown threshold, and achieves an outstanding charge density of 396.50 µC m−2 ...
Hanpeng Gao +7 more
wiley +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
Advanced Science, EarlyView.The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source
Fertility and family policy in Norway - A reflection on trends and possible connections
Demographic Research, 2004 Below replacement fertility in many countries has lead to a renewed public interest in policies that may encourage young people to have more children. The Nordic countries are sometimes in focus in this respect, as their fertility rates remain relatively
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