Results 141 to 150 of about 632,459 (310)
Advanced Science, EarlyView.Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
Grandparents raising grandchildren: towards recognition, respect and reward [PDF]
, 2013 Executive Summary: Grandparents have long played a major role in the lives of their children and grandchildren, with some providing extensive emotional, material and practical support.
Deborah Brennan
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Discover Public HealthIntroduction Tobacco use is a leading preventable cause of morbidity and mortality worldwide, with initiation often occurring during adolescence. Early uptake increases the risk of lifelong addiction and non-communicable diseases.
Wingston Felix Ng’ambi +2 more
doaj +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
Advanced Science, EarlyView.WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Ten policy principles for a national system of early childhood education and care
, 2007 Australia needs a new nationally coordinated, planned approach to an integrated system of early childhood education and care is the concensus of a national workshop on childcare held in 2006.
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Advanced Electronic Materials, EarlyView.Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley +1 more source
Civic integration of the third-country nationals nationalism versus Europeanisation in the common EU immigration policy. CEPS Liberty and Secuiry in Europe, October 2009 [PDF]
, 2009 'Civic integration' programmes and tests for third-country nationals (TCNs) have increasingly become part of member states’ legislation implementing EC immigration law and the EU Framework on Integration.
Carrera, S. +3 more
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Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries
Advanced Energy Materials, EarlyView.This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee +3 more
wiley +1 more source
Molecular Design Strategies for High‐Voltage Organic Cathodes
Advanced Energy Materials, EarlyView.This work proposes molecular engineering strategies for high‐voltage organic cathode materials for Li‐ion batteries: (1) increase Li‐O coordination number (CN), (2) achieve a greater increase in aromaticity upon reduction (∆Aromaticity), and (3) add an electron‐withdrawing group (EWG), through a combined experimental and computational study on reported
Sungil Hong +8 more
wiley +1 more source
The National Children Policy Kenya 2010
, 2010 This policy defines a child as any person under the age of 18 years. Children hold a special place in society. Their nurture and well being is the responsibility of key stakeholders who include parents, wider family, the state (central and local ...
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