Results 131 to 140 of about 10,049,210 (380)
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source
Automating System Test Case Classification and Prioritization for Use Case-Driven Testing in Product Lines [PDF]
arXiv, 2019 Product Line Engineering (PLE) is a crucial practice in many software development environments where software systems are complex and developed for multiple customers with varying needs. At the same time, many development processes are use case-driven and this strongly influences their requirements engineering and system testing practices.
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022 Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley +1 more source
Exponential Family Hybrid Semi-Supervised Learning [PDF]
Twenty-First International Joint Conference on Artificial
Intelligence 2009, pg 974-979, 2010 We present an approach to semi-supervised learning based on an exponential family characterization. Our approach generalizes previous work on coupled priors for hybrid generative/discriminative models. Our model is more flexible and natural than previous approaches.
arxiv
South African Family Practice, 2006 CPD EditorialThis issue of SA Family Practice includes a wide variety of topics – typically what is seen and experienced in practice everyday. The first article describes a prediction rule for short-term (within 7 days) stroke prediction after a transient ischaemic attack (TIA).
Gboyega A Ogunbanjo, Douw Greeff
openaire +2 more sources
Book Review: Family Counseling: Practice and Teaching [PDF]
, 1950 Else Jockel
openalex +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022 Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino +16 more
wiley +1 more source
BMC Musculoskeletal Disorders, 2018 Background Knowledge on prevalence of osteoporosis stratifying for socioeconomic background is insufficient in Germany. Little is known in Europe about other diseases that go along with it although these aspects are important for implementing effective ...
Marie-Therese Puth +4 more
doaj +1 more source