Results 131 to 140 of about 4,362,522 (358)
A review of published research in the South African Family Practice - A clarion call to action. [PDF]
Von Pressentin KB+3 more
europepmc +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
wiley +1 more source
"May you live in interesting times" [PDF]
It is an honour for me to be invited to write this guest editorial on the field of family practice as the new president of the Malta College of Family Doctors, which was established audaciously and courageously some fourteen years ago, those involved ...
Mallia, Pierre
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In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source
Scope of work and the future of family practice. [PDF]
Lemire F, Slade S.
europepmc +1 more source
Is the Ambulatory Care Educational Program for Trainees of Residency Program Adequate to Meet Their Post-Training Clinical Performance Needs?: Assessment in Family Practice Residency Program of Tertiary Hospital [PDF]
Joon Seo Yoo+5 more
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Christian Family as Domestic Church in the Writings of St. John Chrysostom [PDF]
Translated by Wacław GrzybowskiJohn Chrysostom, the most famous preacher of the Eastern Empire, exerted an important influence on the formation of family.
Widok, Norbert
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