Results 71 to 80 of about 8,832,657 (301)

Effectiveness of treatment of newly diagnosed hypertension in family medicine practices in South Croatia

BMC Family Practice, 2019
Background Uncontrolled blood pressure remains an urgent issue in clinical practice worldwide. This study aimed to compare the characteristics and effectiveness of hypertension control in family medicine pratice in the first treatment year, in relation ...
Diana Jurić, Ivančica Pavličević, Ana Marušić, Mario Malički, Ivan Buljan, Velen Šarotić, Nataša Mrduljaš-Đujić, Ante Komparak, Miona Vujević, Danijela De Micheli-Vitturi, Pjera Šušnjar, Tina Puljiz, Minka Jerčić, Dario Leskur, Matko Marušić   +14 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

JMCFD [PDF]

, 2013
Contents: Accreditation by the Royal College of General Practitioners - Pierre Mallia; MCFD Education secretariat - Doreen CassarThe mission of the Journal of the Malta College of Family Doctors (JMCFD) is to deliver accurate, relevant and inspiring ...
Mallia, Pierre, Malta College of Family Doctors, Agius, Dominic   +2 more
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Patient perspectives on stress after ICU and a short primary care based psychological intervention – results from a qualitative sub‑study of the PICTURE trial

BMC Primary Care
Background Approximately 20–25% of patients who survive medical treatment at an intensive care unit (ICU) develop post-traumatic stress symptoms. There is currently a gap in follow-up care for them.
Antina Beutel, Linda Sanftenberg, Chris M. Friemel, Robert Philipp Kosilek, Maggie Schauer, Thomas Elbert, Ulf-Dietrich Reips, Tomke Schubert, Sabine Gehrke-Beck, Konrad Schmidt, Jochen Gensichen, for the PICTURE study group   +11 more
doaj   +1 more source

Dealing with health literacy at the organisational level, French translation and adaptation of the Vienna health literate organisation self-assessment tool

BMC Health Services Research, 2019
Background Efforts to address health literacy should favour a system-based approach with the dual aim both of fostering the material conditions and creating a work culture inside health care organisations that makes it easier for people to use ...
Gilles Henrard, Marc Vanmeerbeek, Laetitia Buret, Jany Rademakers   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Creating Meaning in Family Medicine

Introduction: Burnout syndrome continues to pose a risk to physicians, patients and the healthcare system. Finding meaning in one’s work has been shown to act as a protective factor against burnout.
Conradi, Una, Default Account, Family Practice Resident   +1 more
core   +1 more source

A before-after study of hospital use in two frail populations receiving different home-based services over the same time in Vancouver, Canada

BMC Health Services Research, 2018
Background As individuals age, they are more likely to experience increasing frailty and more frequent use of hospital services. First, we explored whether initiating home-based primary care in a frail homebound cohort, influenced hospital use.
Margaret J. McGregor, Michelle B. Cox, Jay M. Slater, Jeff Poss, Kimberlyn M. McGrail, Lisa A. Ronald, John Sloan, Michael Schulzer   +7 more
doaj   +1 more source