Results 81 to 90 of about 4,688,064 (316)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
BMC Health Services Research, 2018 Background As individuals age, they are more likely to experience increasing frailty and more frequent use of hospital services. First, we explored whether initiating home-based primary care in a frail homebound cohort, influenced hospital use.
Margaret J. McGregor +7 more
doaj +1 more source
Social workers' perspectives : how can children and young people who have had contact with both Care and Protection and Mental Health Services be supported to experience positive outcomes? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Social Work at Massey University, Manawatu, New Zealand [PDF]
, 2018 This thesis explored social workers’ perspectives on how children and young people who have had contact with both care and protection and mental health services can be supported to experience positive outcomes.
Mounter, Jessica
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
BMC Primary CareBackground Approximately 20–25% of patients who survive medical treatment at an intensive care unit (ICU) develop post-traumatic stress symptoms. There is currently a gap in follow-up care for them.
Antina Beutel +11 more
doaj +1 more source
The Joy of Family Practice [PDF]
The Annals of Family Medicine, 2012 Many family physicians have written about how they influence, nurture, and empower people in their communities of practice. In this essay, the author writes of the personal joys that family medicine has brought him. An expression of his appreciation for his work as a family doctor, it touches on 6 themes that continue to rejuvenate his practice: love ...
openaire +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Academic family practice [PDF]
Family Practice, 2003 In many countries, the imperatives of service delivery, the constraints of shrinking resources and the increasing demands of a well-informed yet frequently risk-taking population conspire to threaten the viability of clinical academic medicine. In many countries, Academies are looking hard at ways of making clinical academic careers more appealing and ...
openaire +3 more sources
Autonomy versus futility? Barriers to good clinical practice in end-of-life care: a Queensland case [PDF]
, 2012 Findings from a Queensland coronial inquest highlight the complex clinical, ethical and legal issues that arise in end-of-life care when clinicians and family members disagree about a diagnosis of clinical futility.
Lawrence, Sean +5 more
core +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source