Results 81 to 90 of about 9,149,435 (259)

German general practitioners’ self-reported management of patients with chronic depression

open access: yesBMC Psychiatry, 2017
Background Patients with chronic depression (persisting symptoms for ≥2 years) are a clinically relevant group with extensive (co)morbidity, high functional impairment and associated costs in primary care. The General Practitioner (GP) is the main health
Florian Wolf   +7 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Building family/general practice research capacity

open access: yes, 2004
To promote the range of interventions for building family/general practice (family medicine) research capacity, we describe successful international examples.
Askew, D., Del Mar, C.
core   +1 more source

CONCUSSION IN FAMILY PRACTICE - A QUICK-REFERENCE GUIDE TO ASSESSMENT AND MANAGEMENT OF CONCUSSION IN ADULTS by David Luu

open access: yes
INTRODUCTION: Although concussions affect hundreds of thousands of Canadians per year, and patients rely on family physicians for initial assessment and follow up, family physicians in Canada often demonstrate a lack of knowledge of the current clinic ...
Luu, David   +1 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Partnership with Families Across the Lifespan: Facilitating Family Nursing Workshop

open access: yes, 2021
Australian and New Zealand nursing practice has a focus on partnership in health care. Family partnership develops through therapeutic family conversations, family assessment, engagement in decision making, understanding and promoting health literacy ...
Rands, Hazel   +2 more
core  

Promoting and inhibiting factors for the implementation of evidence-based non-invasive treatment programs for patients with knee- and/or hip-osteoarthritis: a rapid review

open access: yesBMC Health Services Research
Background Osteoarthritis of the knee and/or hip joint are common conditions among older adults. Although multimodal therapy combining patient education, exercises and weight loss has proven effective, only a few countries offer implemented treatment ...
Jennifer Bosompem   +6 more
doaj   +1 more source

Does one have to be queer to care for queer patients? A qualitative interview study with general practitioners in Germany

open access: yesEuropean Journal of General Practice
Background LGBT* (lesbian, gay, bisexual, trans, others) individuals are known to experience poorer health and restricted access to healthcare compared to cisgender-heterosexual individuals.Objective As General Practitioners (GPs) are a patient’s first ...
Malte Radde   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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