Results 101 to 110 of about 8,832,657 (301)

Professional development of medical students – piloting a longitudinal curriculum at Jena University Hospital (LongProf)

GMS Journal for Medical Education
Background: Professionalism is an important prerequisite for the quality of medical care with specific competencies anchored in the National Competence-Based Learning Objectives Catalogue Medicine 2.0.
Schmidt, Konrad, Siller, Katharina, Rißmann, Jens, Andlauer, Marie, Feustel, Jana, Klein, Friederike, Petruschke, Inga, Schulz, Sven   +7 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Development and implementation of a treatment pathway to reduce coronary angiograms - lessons from a failure

BMC Health Services Research
Background The rates of coronary angiograms (CA) and related procedures (percutaneous intervention [PCI]) are significantly higher in Germany than in other Organisation for Economic Co-ordination and Development (OECD) countries.
Jutta Jung-Henrich, Kathrin Schlößler, Til Uebel, Nino Chikhradze, Anastasia Suslow, Nicole Lindner, Sandra Fahrenkrog, Judith Kraft, Eva Hummers, Horst Christian Vollmar, Ildikó Gágyor, Dirk Heider, Hans-Helmut König, Norbert Donner-Banzhoff   +13 more
doaj   +1 more source

An overview of developing clinical prediction models in family practice

Clinical prediction models are rapidly gaining recognition as valuable tools for enhancing decision-making in family practice. This is driven by the increasing availability of high-quality, routinely collected data.
Manski-Nankervis, Jo Anne Anne E., Chondros, Patty, Thuraisingam, Sharmala, Dowsey, Michelle M., Garies, Stephanie, Black, Jason Edward, Williamson, Tyler S.   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Influence of general practice education on medical students’ attitude towards this discipline: a mixed studies scoping review protocol

BMJ Open
Introduction The shortage of general practitioners in many countries remains a persistent issue and is likely to become more severe in the future. Multiple factors influencing the attitude of medical students towards general practice have been identified.
Christiane Muth, Tim Peters, Lara Schürmann, Svetlana Puzhko, Lea-Mareen Höft, Julia Karpfinger, Stephan Gerbaulet, Julia Sternal, Bettina Leeuw   +8 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Family physician and family medicine resident perspectives on physician payment model in British Columbia.

Key Words: LFP, Payment Model, Remuneration   Introduction: In British Columbia, there are various payment models available for family physicians, including Fee for Service, Alternative Payment Programs and various contracts.
Geum, Liz, Hage, Ramzy, Waraich, Roop, Default Account, Family Practice Resident, Rezaei, Sajjad   +4 more
core   +1 more source

The effects of perceived chronic stress and work-related factors on the risk of incident depression among German general practice personnel: a causal pathway approach using IMPROVEjob study data

BMC Public Health
Background The increasing workload faced by general practitioners (GPs) and practice assistants (PrAs) contributes to chronic stress and heightens the risk of depression.
Arezoo Bozorgmehr, Mona Ahmed, Julian Göbel, Benjamin Aretz, Birgitta Weltermann   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source