Results 101 to 110 of about 4,660,425 (301)

Shared Care, Elder and Family Member Skills Used to Manage Burden [PDF]

, 2005
Aim. The aim of this paper is to further develop the construct of Shared Care by comparing and contrasting it to related research, and to show how the construct can be used to guide research and practice. Background.
AhYun K., Aneshensel C.S., Archbold P.G., Archbold P.G., Davey A., Deimling G.T., Feinberg L.F., Gayle B.M., Gayle B.M., Germino B., Grady K.L., Hooker K., Horowitz A., Leventhal H., Lincoln Y.S., Lyons K.S., Poole M.S., Pruchno R.A., Pruchno R.A., Reinardy J.R., Rook K., Schwartz-Barcott D., Schwartz-Barcott D., Smerglia V.L., Stone D., Thomas V., Walker A.J., Wolff J.L., World Health Organization   +28 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Does one have to be queer to care for queer patients? A qualitative interview study with general practitioners in Germany

European Journal of General Practice
Background LGBT* (lesbian, gay, bisexual, trans, others) individuals are known to experience poorer health and restricted access to healthcare compared to cisgender-heterosexual individuals.Objective As General Practitioners (GPs) are a patient’s first ...
Malte Radde, Philip Oeser, Anna Sophia Wittenstein, Eric Blumenauer, Marc Sebastian Melz, Wolfram J. Herrmann   +5 more
doaj   +1 more source

Practitioners\u27 Views of Family Strengths: A Delphi Study [PDF]

, 2011
Reported is a research study to assess the opinions of family practitioners on the status of families in Oklahoma. Researchers employed the Delphi method to achieve consensus among key informants in the family practice field about the strengths and ...
Crowder, Jessica, Romero, Kathleen, Wedel, Kenneth   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Development and implementation of a treatment pathway to reduce coronary angiograms - lessons from a failure

BMC Health Services Research
Background The rates of coronary angiograms (CA) and related procedures (percutaneous intervention [PCI]) are significantly higher in Germany than in other Organisation for Economic Co-ordination and Development (OECD) countries.
Jutta Jung-Henrich, Kathrin Schlößler, Til Uebel, Nino Chikhradze, Anastasia Suslow, Nicole Lindner, Sandra Fahrenkrog, Judith Kraft, Eva Hummers, Horst Christian Vollmar, Ildikó Gágyor, Dirk Heider, Hans-Helmut König, Norbert Donner-Banzhoff   +13 more
doaj   +1 more source

Assessment of motivational interviewing: a qualitative study of response process validity, content validity and feasibility of the motivational interviewing target scheme (MITS) in general practice

BMC Medical Education, 2017
Background The Motivational Interviewing target Scheme (MITS) is an instrument to assess competency in Motivational Interviewing (MI) and can be used to assess MI in long and brief consultations.
Riëtta Oberink, Saskia M. Boom, Nynke van Dijk, Mechteld R. M. Visser   +3 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Family Home Visiting Service in South Australia -Translating the evidence into practice [PDF]

, 2006
There continues to accumulate an abundance of evidence demonstrating the importance of the early years of life to a child\u27s development and later adult functioning.
Nossar, Victor
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source