Results 91 to 100 of about 4,660,425 (301)

The imaginary of the name [PDF]

open access: yes, 2005
In wide areas, including Albania, names were fixed as patronymics and family surnames, showing that their context fluctuation is related to a relative transmissible fixity which must make possible an instrumental politics in naming practice as well as
Doja, A.
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Social workers' perspectives : how can children and young people who have had contact with both Care and Protection and Mental Health Services be supported to experience positive outcomes? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Social Work at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2018
This thesis explored social workers’ perspectives on how children and young people who have had contact with both care and protection and mental health services can be supported to experience positive outcomes.
Mounter, Jessica
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Promoting and inhibiting factors for the implementation of evidence-based non-invasive treatment programs for patients with knee- and/or hip-osteoarthritis: a rapid review

open access: yesBMC Health Services Research
Background Osteoarthritis of the knee and/or hip joint are common conditions among older adults. Although multimodal therapy combining patient education, exercises and weight loss has proven effective, only a few countries offer implemented treatment ...
Jennifer Bosompem   +6 more
doaj   +1 more source

Education in Family Medicine : What has been achieved? [PDF]

open access: yes, 2012
Contents: Education... historical landmarks - Pierre Mallia; The Malta College of Family Doctors and the Royal College of General Practitioners - John V.
Agius, Dominic   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Professional development of medical students – piloting a longitudinal curriculum at Jena University Hospital (LongProf)

open access: yesGMS Journal for Medical Education
Background: Professionalism is an important prerequisite for the quality of medical care with specific competencies anchored in the National Competence-Based Learning Objectives Catalogue Medicine 2.0.
Schmidt, Konrad   +7 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

South African Family Practice incorporating Geneeskunde!

open access: yesSouth African Family Practice, 2003
No abstract available.
Pierre J.T. de Villiers, Douw Greef
doaj   +1 more source

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