Results 91 to 100 of about 4,688,064 (316)

Dealing with health literacy at the organisational level, French translation and adaptation of the Vienna health literate organisation self-assessment tool

open access: yesBMC Health Services Research, 2019
Background Efforts to address health literacy should favour a system-based approach with the dual aim both of fostering the material conditions and creating a work culture inside health care organisations that makes it easier for people to use ...
Gilles Henrard   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Practitioners\u27 Views of Family Strengths: A Delphi Study [PDF]

open access: yes, 2011
Reported is a research study to assess the opinions of family practitioners on the status of families in Oklahoma. Researchers employed the Delphi method to achieve consensus among key informants in the family practice field about the strengths and ...
Crowder, Jessica   +2 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Diagnostic accuracy of artificial intelligence compared to family physicians and dermatologists for skin conditions: a systematic review and meta-analysis

open access: yesBMC Primary Care
Context Artificial intelligence (AI) technologies are increasingly used for image recognition, especially for skin lesions. Due to what may be long wait times for dermatology appointments, general practitioners (GPs) are the gatekeepers when it comes to ...
Norhane Nadour   +4 more
doaj   +1 more source

German general practitioners’ self-reported management of patients with chronic depression

open access: yesBMC Psychiatry, 2017
Background Patients with chronic depression (persisting symptoms for ≥2 years) are a clinically relevant group with extensive (co)morbidity, high functional impairment and associated costs in primary care. The General Practitioner (GP) is the main health
Florian Wolf   +7 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The family in the practices of Family Health teams

open access: yesRevista Brasileira de Enfermagem, 2014
Exploratory, qualitative study, that aimed to analyze the "centrality in the family", a Family Health Strategy (FHS) attribute, examining how the family context is considered in the practice of health professionals, through the analysis of health practices directed to families in Manaus-AM, Brazil.
Nair Chase, da Silva   +2 more
openaire   +2 more sources

The imaginary of the name [PDF]

open access: yes, 2005
In wide areas, including Albania, names were fixed as patronymics and family surnames, showing that their context fluctuation is related to a relative transmissible fixity which must make possible an instrumental politics in naming practice as well as
Doja, A.
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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