Results 101 to 110 of about 2,467,323 (353)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Marital and family therapy

open access: yesIndian Journal of Psychiatry, 2019
Substance abuse is a family disease that adversely impacts both the user and the user's family. The family can act as a risk factor for the development of substance abuse among children and adults.
Hargun Ahluwalia   +2 more
doaj   +1 more source

Effectiveness of blood pressure control in a small community [PDF]

open access: yes, 1989
The aim of this study was to examine the degree of control of blood pressure with respect to individuals on anti-hypertensive drug therapy attending a Health Centre for repeat prescription.
Cacciottolo, Joseph M., Galea, Wilfred
core  

Risk marker associations with venous thrombotic events: a cross-sectional analysis. [PDF]

open access: yes, 2014
ObjectiveTo examine the interrelations among, and risk marker associations for, superficial and deep venous events-superficial venous thrombosis (SVT), deep venous thrombosis (DVT) and pulmonary embolism (PE).DesignCross-sectional analysis.SettingSan ...
Chan, Virginia T   +4 more
core   +1 more source

A family‐therapy approach to child abuse: countering resistance [PDF]

open access: bronze, 1983
Peter Dale   +4 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Does Caregiver Engagement Predict Outcomes of Adolescent Wilderness Therapy?

open access: yesBehavioral Sciences
Existing research shows some links between wilderness therapy outcomes and familial functioning. However, wilderness therapy programs do not agree on what kind of caregiver involvement is required to improve adolescent program outcomes, nor has research ...
Joanna E. Bettmann   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Suicide and the Coloniality of the Senses, Time, and Being: The Aesthetics of Death Desires

open access: yesSocial Sciences
We engage the decolonial option from Abya Yala, el Caribe, and Eastern Europe with an interest in suicide from our struggles as racialized people and our dehumanization, whereby, for many of us, suicide is not an act of autonomy or resistance but the ...
marcela polanco, Anthony Pham
doaj   +1 more source

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