Results 71 to 80 of about 5,398 (210)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Examining the significance of the digital personal data protection act, 2023 in the context of the healthcare industry: a comprehensive analysis

open access: yesDiscover Public Health
With the increasing digitization of health records and telemedicine, safeguarding sensitive health data has become paramount. The Digital Personal Data Protection Act, 2023 (DPDP Act) marks a transformative step in India’s data privacy landscape ...
Vasudha Khanna, Atul Kotwal
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Strengthening India’s health systems through civil registration reforms

open access: yesDiscover Public Health
A robust Civil Registration System (CRS) forms the backbone of effective governance and national development, providing critical data for planning and policymaking.
Vasudha Khanna, Atul Kotwal
doaj   +1 more source

AI-CAD enhances pulmonary TB detection and yield in active case finding

open access: yesIJTLD Open
BACKGROUND: India accounts for 27% of global TB incidence and bears the highest TB burden worldwide. This study evaluates the performance of an AI-assisted computer-aided detection (AI-CAD) solution in a community-based, active case-finding TB screening ...
A. Frederick   +8 more
doaj   +1 more source

Fragile Families and Welfare Reform [PDF]

open access: yesChildren and Youth Services Review, 2001
Irwin Garfinkel, Sara McLanahan
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Study Of Prevalence of Fluorosis in Endemic Village of Kankar District of Chhattisgarh State, India

open access: yesNational Journal of Community Medicine, 2014
Background: Endemic fluorosis is an important public health problem in certain pockets of Chhattisgarh. Fluorosis is caused by exposure to a continuous high level of fluoride for a long time leads to dental and skeletal deformities.
Sunil V Gitte   +2 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Innovation and nutritional content analysis in making Kue Lumpur using green broccoli (Brassica oleracea var. italica) puree as substitute ingredient

open access: yesAcTion: Aceh Nutrition Journal
Broccoli is abundant in fiber, vitamins, and minerals and is useful as a complement to main dishes. However, the use of broccoli during baking is still limited.
Andi Hudiah   +3 more
doaj   +1 more source

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