Results 41 to 50 of about 66,919 (281)

The relationship between famine exposure during early life and body mass index in adulthood: A systematic review and meta-analysis.

PLoS ONE, 2018
BackgroundPrevious epidemiologic studies have reported famine exposure during early life association with overweight or obesity in adulthood, but a consistent perspective has not been established to date.PurposeTo determine, by conducting a systematic ...
Jielin Zhou, Liangjian Zhang, Peng Xuan, Yong Fan, Linsheng Yang, Chunqiu Hu, Qingli Bo, Guoxiu Wang, Jie Sheng, Sufang Wang   +9 more
doaj   +1 more source

The association between prenatal famine, DNA methylation and mental disorders: a systematic review and meta-analysis

Clinical Epigenetics, 2023
Background Undernutrition in pregnant women is an unfavorable environmental condition that can affect the intrauterine development via epigenetic mechanisms and thus have long-lasting detrimental consequences for the mental health of the offspring later ...
Heike Eichenauer, Ulrike Ehlert
doaj   +1 more source

Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes

Frontiers in Neuroscience, 2022
Persons with type 2 diabetes born in the regions of famine exposures have disproportionally elevated risk of vision-threatening proliferative diabetic retinopathy (PDR) in adulthood. However, the underlying mechanisms are not known. In the present study,
Olena Fedotkina, Ruchi Jain, Rashmi B. Prasad, Andrea Luk, Marta García-Ramírez, Türküler Özgümüs, Liubov Cherviakova, Nadiya Khalimon, Tetiana Svietleisha, Tetiana Buldenko, Victor Kravchenko, Deepak Jain, Allan Vaag, Juliana Chan, Mykola D. Khalangot, Mykola D. Khalangot, Cristina Hernández, Peter M. Nilsson, Rafael Simo, Isabella Artner, Valeriya Lyssenko, Valeriya Lyssenko   +21 more
doaj   +1 more source

Childhood Health Status and Adulthood Cardiovascular Disease Morbidity in Rural China: Are They Related? [PDF]

, 2016
Cardiovascular diseases (CVDs) are among the top health problems of the Chinese population. Although mounting evidence suggests that early childhood health status has an enduring effect on late life chronic morbidity, no study so far has analyzed the ...
Shen, Jay, Wang, Qing
core   +3 more sources

Cardiovascular and cortisol reactions to acute psychological stress and cognitive ability in the Dutch Famine Birth Cohort Study [PDF]

, 2011
Objective: Recently, in analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed.
al'Absi, al'Absi, al'Absi, Backs, Bakker, Balanos, Barnett, Blair, Busato, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Deary, DeGangi, deRooij, deRooij, deRooij, Domes, Duschek, Dweck, Elias, Elias, Everson, Georgiades, Ginty, Girdler, Heaney, Heim, Kapuku, Koo-Loeb, Launer, Lovallo, Lovallo, Lupien, Lynch, Markovitz, Matthews, Matthews, McClelland, Murdison, Newman, Novak, Painter, Panknin, Phillips, Phillips, Phillips, Pintrich, Pruessner, Rabbitt, Ravelli, Robbins, Rottenberg, Roy, Salomon, Singh-Manoux, Sloan, Waldstein, Waldstein, Waldstein, Wolf, Wood, Wright, York   +67 more
core   +1 more source

Early-life exposure to Chinese famine and stroke risk in mid- to late life: the mediating roles of cognitive function and depression

BMC Geriatrics, 2022
Background Limited research has examined the role that famine exposure plays in adulthood stroke risk. We aim to explore the causal implications of early exposure to the Great Chinese Famine on stroke risk and determine whether these associations were ...
Zi Zhou, Wei Zhang, Ya Fang
doaj   +1 more source

DNA methylation signatures link prenatal famine exposure to growth and metabolism [PDF]

Nature Communications, 2014
AbstractPericonceptional diet may persistently influence DNA methylation levels with phenotypic consequences. However, a comprehensive assessment of the characteristics of prenatal malnutrition-associated differentially methylated regions (P-DMRs) is lacking in humans.
Tobi, E.W., Goeman, J.J., Monajemi, R., Gu, H.C., Putter, H., Zhang, Y.J., Slieker, R.C., Stok, A.P., Thijssen, P.E., Muller, F., Zwet, E.W. van, Bock, C., Meissner, A., Lumey, L.H., Slagboom, P.E., Heijmans, B.T.   +15 more
openaire   +7 more sources

Famine in the young and risk of later hospitalization for COPD and asthma. [PDF]

PLoS ONE, 2013
BACKGROUND: Undernutrition during critical periods of growth and development may permanently affect lung physiology and function. OBJECTIVES: To investigate whether acute undernutrition in childhood or young adulthood increases the risk of later ...
Annet F M van Abeelen, Sjoerd G Elias, Pim A de Jong, Diederick E Grobbee, Patrick M M Bossuyt, Yvonne T van der Schouw, Tessa J Roseboom, Cuno S P M Uiterwaal   +7 more
doaj   +1 more source

Increase in the prevalence of hypertension among adults exposed to the Great Chinese Famine during early life

Environmental Health and Preventive Medicine, 2017
Objective This study aimed to assess the association between exposure to the Great Chinese Famine (1959–1961) during early life and hypertension in adulthood.
Lingli Liu, Xianglong Xu, Huan Zeng, Yong Zhang, Zumin Shi, Fan Zhang, Xianqing Cao, Yao Jie Xie, Cesar Reis, Yong Zhao   +9 more
doaj   +1 more source

Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort [PDF]

, 2013
Data from epidemiological and animal model studies suggest that nutrition during pregnancy may affect the health status of subsequent generations. These transgenerational effects are now being explained by disruptions at the level of the epigenetic ...
A Kerjean, A Murrell, A Soubry, AD Stein, Adelheid Soubry, Amy Murtha, AP Feinberg, Autumn Bernal, BE Levin, BR Carone, BT Heijmans, C Gemma, C Gicquel, C Hoyo, C Hoyo, Cathrine Hoyo, CC Boissonnas, DC Dolinoy, DC Dolinoy, DJ Barker, Frances Wang, G Kaati, GA Dunn, GP Ravelli, H Boerschmann, H Cui, H Cui, H Cui, J Baker, J Frystyk, JA McKay, Joanne Kurtzberg, Joellen M Schildkraut, JS Dyer, KJ Stothard, LM McCowan, M Braunschweig, M Cruz-Correa, M Ollikainen, ME Pembrey, ME Pembrey, MJ Steenman, MJ Sullivan, Q Wu, R Barres, R Figueroa-Colon, R Loomba, RA Waterland, RA Waterland, RA Waterland, Randy L Jirtle, RC Painter, RC Painter, RL Jirtle, RP Steegers-Theunissen, S Honda, S Katari, S Pathak, SA Tanumihardjo, SD McDonald, SF Ng, SK Murphy, SK Murphy, SK Murphy, SS Du Plessis, Susan K Murphy, W Chao, Z Huang, Zhiqing Huang   +68 more
core   +3 more sources