Results 41 to 50 of about 328 (208)

Early-life famine exposure increases the risk of subsequent physical disability: evidence from a national population-based survey

Frontiers in Public Health
BackgroundDue to ethical constraints, famines, which can lead to severe malnutrition, are often viewed as natural experiments to assess the impact of early-life nutritional malnutrition on adverse health outcomes in adulthood. However, evidence regarding
Shiwei Cao, Yao Wu, Tengfei Niu, Xiyu Chen, Jie Xiang, Hao Li, Ziyi Chen, Qianying Shi, Yu Du, Yu Du   +9 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Exposure to different severities of famine and subsequent risk of sarcopenia in old age

Journal of Nutritional Oncology
. Background. Poor nutritional status is closely related to the development of sarcopenia and possible sarcopenia. Limited articles have evaluated the impact of undernutrition at different stages of life on the development of sarcopenia or possible ...
Miao-Miao Lu, Yu-Wei Zhou, Xi Jin
doaj   +1 more source

Fetal Exposure to Chinese Famine Increases Obesity Risk in Adulthood [PDF]

International Journal of Environmental Research and Public Health, 2020
Fetal exposure to famine may have long-term consequences in adulthood. The purpose of the present study was to explore the association between famine exposure in fetal life (Chinese famine in 1959–1961) and obesity risk in adulthood. A total of 8054 subjects (3422 male, 4632 female) were recruited from the cross-sectional 2010–2012 China National ...
Chao Song, Meng Wang, Zheng Chen, Yecheng Yao, Ganyu Feng, Yanning Ma, Jing Fan, Ailing Liu   +7 more
openaire   +2 more sources

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Early-life famine exposure, genetic susceptibility and risk of MAFLD in adulthood

The Journal of Nutrition, Health and Aging
Objectives: Early-famine exposure was reported to be associated with metabolic associated fatty liver disease (MAFLD); however, it has not been fully elucidated whether the gene-famine interaction exist in this association.
Yuying Wang, Kun Zhang, Bin Wang, Bowei Yu, Ziteng Zhang, Yuetian Yu, Yuefeng Yu, Ying Sun, Yi Chen, Wen Zhang, Yan Cai, Qian Xiang, Fangzhen Xia, Ningjian Wang, Yingli Lu   +14 more
doaj   +1 more source

Association between exposure to the Chinese Famine in different stages of early life and decline in cognitive functioning in adulthood

Frontiers in Behavioral Neuroscience, 2016
Objective: To investigate whether exposure to the Chinese Famine in different life stages of early life is associated with cognitive functioning decline in adulthood.Methods: We recruited 1366 adults born between 1952 and 1964 and divided them into fetal-
Chao Wang, Yu An, Huanling Yu, Lingli Feng, Quanri Liu, Yanhui Lu, Hui Wang, Rong Xiao   +7 more
doaj   +1 more source

Adolescence exposure to China’s great famine period and the association of metabolic syndrome in adulthood: a retrospective study

BMC Public Health, 2022
Background Exposure to famine during early life is related to several adverse health outcomes in adulthood, but the effect of famine exposure during adolescence is unclear.
Ning Sun, Wei Li, Olatokunbo Osibogun, Mohammad Ebrahimi Kalan, Rime Jebai, Prem Gautam, Tanjila Taskin, Wupeng Yin, Jeffery A. Jones, Michelle Gamber, Wenjie Sun   +10 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Concurrency of Early-Age Exposure to Chinese Famine and Diabetes Increases Recurrence of Ischemic Stroke

Frontiers in Neurology, 2021
Background and Purpose: Early age exposure to the Chinese Great Leap Forward famine (1959–1961) is associated with the incidence of risk factors for ischemic stroke.
Yue Suo, Yue Suo, Yue Suo, Yue Suo, Weiqi Chen, Weiqi Chen, Weiqi Chen, Weiqi Chen, Yuesong Pan, Yuesong Pan, Yuesong Pan, Yuesong Pan, Hao Li, Hao Li, Hao Li, Hao Li, Xia Meng, Xia Meng, Xia Meng, Xia Meng, Zixiao Li, Zixiao Li, Zixiao Li, Zixiao Li, Chunjuan Wang, Chunjuan Wang, Chunjuan Wang, Chunjuan Wang, Jing Jing, Jing Jing, Jing Jing, Jing Jing, Yilong Wang, Yilong Wang, Yilong Wang, Yilong Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang   +39 more
doaj   +1 more source