Results 51 to 60 of about 7,777 (264)

The association between prenatal famine, DNA methylation and mental disorders: a systematic review and meta-analysis

Clinical Epigenetics, 2023
Background Undernutrition in pregnant women is an unfavorable environmental condition that can affect the intrauterine development via epigenetic mechanisms and thus have long-lasting detrimental consequences for the mental health of the offspring later ...
Heike Eichenauer, Ulrike Ehlert
doaj   +1 more source

The relationship between famine exposure during early life and body mass index in adulthood: A systematic review and meta-analysis.

PLoS ONE, 2018
BackgroundPrevious epidemiologic studies have reported famine exposure during early life association with overweight or obesity in adulthood, but a consistent perspective has not been established to date.PurposeTo determine, by conducting a systematic ...
Jielin Zhou, Liangjian Zhang, Peng Xuan, Yong Fan, Linsheng Yang, Chunqiu Hu, Qingli Bo, Guoxiu Wang, Jie Sheng, Sufang Wang   +9 more
doaj   +1 more source

Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes

Frontiers in Neuroscience, 2022
Persons with type 2 diabetes born in the regions of famine exposures have disproportionally elevated risk of vision-threatening proliferative diabetic retinopathy (PDR) in adulthood. However, the underlying mechanisms are not known. In the present study,
Olena Fedotkina, Ruchi Jain, Rashmi B. Prasad, Andrea Luk, Marta García-Ramírez, Türküler Özgümüs, Liubov Cherviakova, Nadiya Khalimon, Tetiana Svietleisha, Tetiana Buldenko, Victor Kravchenko, Deepak Jain, Allan Vaag, Juliana Chan, Mykola D. Khalangot, Mykola D. Khalangot, Cristina Hernández, Peter M. Nilsson, Rafael Simo, Isabella Artner, Valeriya Lyssenko, Valeriya Lyssenko   +21 more
doaj   +1 more source

Early-life exposure to Chinese famine and stroke risk in mid- to late life: the mediating roles of cognitive function and depression

BMC Geriatrics, 2022
Background Limited research has examined the role that famine exposure plays in adulthood stroke risk. We aim to explore the causal implications of early exposure to the Great Chinese Famine on stroke risk and determine whether these associations were ...
Zi Zhou, Wei Zhang, Ya Fang
doaj   +1 more source

Famine in the young and risk of later hospitalization for COPD and asthma. [PDF]

PLoS ONE, 2013
BACKGROUND: Undernutrition during critical periods of growth and development may permanently affect lung physiology and function. OBJECTIVES: To investigate whether acute undernutrition in childhood or young adulthood increases the risk of later ...
Annet F M van Abeelen, Sjoerd G Elias, Pim A de Jong, Diederick E Grobbee, Patrick M M Bossuyt, Yvonne T van der Schouw, Tessa J Roseboom, Cuno S P M Uiterwaal   +7 more
doaj   +1 more source

Increase in the prevalence of hypertension among adults exposed to the Great Chinese Famine during early life

Environmental Health and Preventive Medicine, 2017
Objective This study aimed to assess the association between exposure to the Great Chinese Famine (1959–1961) during early life and hypertension in adulthood.
Lingli Liu, Xianglong Xu, Huan Zeng, Yong Zhang, Zumin Shi, Fan Zhang, Xianqing Cao, Yao Jie Xie, Cesar Reis, Yong Zhao   +9 more
doaj   +1 more source

Exposure to Famine at a Young Age and Unhealthy Lifestyle Behavior Later in Life. [PDF]

PLoS ONE, 2016
BACKGROUND:A healthy diet is important for normal growth and development. Exposure to undernutrition during important developmental periods such as childhood and adolescence can have effects later in life.
Heidi P Fransen, Petra H M Peeters, Joline W J Beulens, Jolanda M A Boer, G Ardine de Wit, N Charlotte Onland-Moret, Yvonne T van der Schouw, H Bas Bueno-de-Mesquita, Jeljer Hoekstra, Sjoerd G Elias, Anne M May   +10 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Adults prenatally exposed to the Dutch Famine exhibit a metabolic signature associated with a broad spectrum of common diseases

BMC Medicine
Background Exposure to famine in the prenatal period is associated with an increased risk of metabolic disease, including obesity and type 2 diabetes. We employed nuclear magnetic resonance (NMR) metabolomic profiling to identify the metabolic changes ...
M. Jazmin Taeubert, Thomas B. Kuipers, Jiayi Zhou, Chihua Li, Shuang Wang, Tian Wang, Elmar W. Tobi, BBMRI-NL Metabolomics consortium, Daniel W. Belsky, L. H. Lumey, Bastiaan T. Heijmans   +10 more
doaj   +1 more source

Adolescence exposure to China’s great famine period and the association of metabolic syndrome in adulthood: a retrospective study

BMC Public Health, 2022
Background Exposure to famine during early life is related to several adverse health outcomes in adulthood, but the effect of famine exposure during adolescence is unclear.
Ning Sun, Wei Li, Olatokunbo Osibogun, Mohammad Ebrahimi Kalan, Rime Jebai, Prem Gautam, Tanjila Taskin, Wupeng Yin, Jeffery A. Jones, Michelle Gamber, Wenjie Sun   +10 more
doaj   +1 more source