Results 71 to 80 of about 726,293 (345)
Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen +13 more
wiley +1 more source
The first Food and Agriculture Organization of the United Nations (FAO) Action Plan on antimicrobial resistance (AMR), published in 2016, identified the need to develop capacity for AMR surveillance and monitoring in food and agriculture sectors. As part
Nicolas Keck +13 more
doaj +1 more source
Towards development of a report on the state of the world's forest genetic resources [PDF]
La disponibilité de données fiables est indispensable pour la conservation efficace et la gestion durable des ressources génétiques forestières. À ce jour, il n'existe aucune vision globale de l'état et de l'évolution de ces ressources, ni d'estimations ...
Palmberg-Lerche, Christel +1 more
core
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong +13 more
wiley +1 more source
Active Protection Technology of Depot Automatic Zones in Urban Rail Transit FAO Vehicle Base
[Objective] Setting up underpass or overpass in front or inside the urban rail transit depot for personnel's access to the automatic zone requires large project investment, being prone to affect personnel evacuation and cause safety hazards due to the ...
Zhengyuan ZHANG
doaj +1 more source
Strategic Review of Tropical Fisheries Management [PDF]
This project addresses the constraints to tropical fisheries development with sustainable exploitation through a strategic assessment of tropical fisheries management with the following purposes: (1) To evaluate relevant research methods for the ...
A. S. Halls +4 more
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Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang +8 more
wiley +1 more source
FAO Training Workshop on "Epidemiology, surveillance, outbreaks investigation and training engineering in epidemiological field", U Choice Hotel, Lunming - China, 29th june-9th july 2009 : Mission report [PDF]
Cet atelier a été organisé par la FAO en collaboration avec le CIRAD et les services vétérinaires chinois. La formation a été divisée en deux parties distinctes: la première avait pour objectif de renforcer les capacités des agents des services ...
Desvaux, Stéphanie +2 more
core
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Use of Indicators to Evaluate Sustainability of Animal Production Systems [PDF]
SUMMARY – Few indicators for sustainability are used in studying animal production systems. Sustainability of these systems should be evaluated in a dynamic and multidisciplinary manner, and those indicators used should allow for detecting the systems'
Castel Genís, José María +3 more
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