Results 171 to 180 of about 4,179 (208)

Intense FAPI Uptake in Inflammation May Mask the Tumor Activity of Pancreatic Cancer in 68Ga-FAPI PET/CT

Clinical Nuclear Medicine, 2020
Abstract Contrast CT revealed diffuse enlargement of the pancreas with a suspicious lesion in the uncinate process in a 57-year-old man who presented with jaundice. 18F-FDG PET/CT showed increased radioactivity in the enlarged pancreas with a nodular lesion with even higher uptake in the uncinate process.
Yaping, Luo, Qingqing, Pan, Wen, Zhang, Fang, Li   +3 more
openaire   +2 more sources

Recent Clinical Implications of FAPI

Clinical Nuclear Medicine
Abstract The fibroblast activation protein (FAP) is a biomarker that is selectively overexpressed on cancer-associated fibroblasts (CAFs) in various types of tumoral tissues and some nonmalignant diseases, including fibrosis, arthritis, cardiovascular, and metabolic diseases.
Mahshid, Kiani, Safura, Jokar, Leila, Hassanzadeh, Hossein, Behnammanesh, Omid, Bavi, Davood, Beiki, Majid, Assadi   +6 more
openaire   +2 more sources

Head-to-head comparison of 68Ga-FT-FAPI with 68Ga-FAPI-04 in patients with gastrointestinal tumors

European Journal of Nuclear Medicine and Molecular Imaging
FT-FAPI (FT, fast treatment) is a new FAP inhibitor with the potential to be used as a drug in boron neutron capture therapy (BNCT). The aim of this prospective study was to compare the diagnostic performance of 68Ga-FT-FAPI and 68Ga-FAPI-04 in patients with gastrointestinal (GI) tumors.The study enrolled patients with histologically confirmed GI ...
Wenhui Ma, Shu Yang, Jiajun Ye, Zhiyong Quan, Mingru Zhang, Guiyu Li, Zifan Zhu, Jia Wang, Taoqi Ma, Junling Wang, Yu Liu, Zhibo Liu, Fei Kang, Jing Wang   +13 more
openaire   +2 more sources

99mTc-FAPI-46 Scan and 177Lu-FAPI-2286 Treatment in a Patient With Nasopharyngeal Carcinoma

Clinical Nuclear Medicine
Abstract We present a 24-year-old man with a history of metastatic nasopharyngeal cancer. Despite receiving standard treatments, including surgery, radiotherapy, and chemotherapy, he has shown progression. Consequently, he has been referred to the nuclear medicine department for theranostic purposes.
Somaye Barashki, Bentolhoda Hadad, Nasrin Raeisi, Kamran Aryana   +3 more
openaire   +2 more sources

68Ga-FAPI and 18F-FAPI PET/CT for detection of nodal metastases prior radical cystectomy in high-risk urothelial carcinoma patients [PDF]

European Journal of Nuclear Medicine and Molecular Imaging
IntroductionTo determine the best therapeutic strategy for muscle-invasive bladder cancer (BC), the accuracy of lymph node staging is of paramount importance.
Gerald Bastian Schulz, Lena M Unterrainer, Sophie C Kunte   +2 more
exaly   +2 more sources

FAPI-avid Lesions in the Brain

Clinical Nuclear Medicine
A 63-year-old man presented with transient global amnesia, urinary incontinence, and a visual field deficit. MRI revealed a heterogeneous mass in the left parieto-occipital lobe, diagnosed as glioblastoma multiforme (GBM). Following craniotomy, chemotherapy with temozolomide and radiotherapy were initiated.
Nasrin Raeisi, Amin Saber Tanha, Farid Jafari Zarrin Ghabaei, Kamran Aryana, Emran Askari   +4 more
openaire   +2 more sources

Theranostic Application of FAPI in Advanced Laryngeal Squamous Cell Carcinoma: 99mTc-FAPI-46 SPECT/CT Guided 177Lu-FAPI-2286 Therapy

Clinical Nuclear Medicine
A 47-year-old man with advanced laryngeal squamous cell carcinoma had received chemotherapy but subsequently developed widespread skeletal metastases identified on bone scintigraphy. He underwent 99m Tc-FAPI-46 SPECT/CT, which demonstrated FAPI uptake in primary laryngeal tumor, cervical soft
Haniye Elahifard, Mohammad Hadi Samadi, Mohsen Saberifar, Yasha Makhdoumi, Atena Aghaee   +4 more
openaire   +1 more source

Elevated 68Ga-FAPI Activity in Leiomyosarcoma

Clinical Nuclear Medicine
Abstract Leiomyosarcoma is an aggressive subtype of soft tissue sarcoma with frequent metastatic relapse after curative surgery. Herein, we report the 68Ga-FAPI PET/CT findings in a 45-year-old woman with leiomyosarcoma. 68Ga-FAPI-04 PET/CT detected increased FAPI uptake in abdominal leiomyosarcoma and liver metastases.
Qixin, Wang, Yue, Zhou, XiaoLiang, Chen
openaire   +2 more sources

Lupus Nephritis Revealed by FAPI PET/CT

Clinical Nuclear Medicine
Abstract A 38-year-old woman received a 68Ga-FAPI-04 PET/CT scan for the evaluation of systemic lupus erythematosus. Diffuse uptake in both kidney parenchyma indicated the presence of lupus nephritis. In addition, an incidental carotid body tumor with increased FAPI uptake was also observed.
Wenjie, Zhang, Zhongzhi, Qi, Guohua, Shen   +2 more
openaire   +2 more sources

Elevated FAPI Activity in an Adult Brodie Abscess

Clinical Nuclear Medicine
Abstract We report an adult Brodie abscess with elevated activity of 18F-FDG and 68Ga-FAPI (fibroblast activating protein inhibitor), mimicking bone metastasis. Our case illustrates that Brodie abscess should also be contemplated in the differential diagnosis of osteolytic lesions with increased 68Ga-FAPI uptake.
Yang, Xie, Wenxin, Tang, Huipan, Liu, Yudi, Wang, Yue, Chen   +4 more
openaire   +2 more sources