Results 31 to 40 of about 3,903,989 (306)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Teaching in The Far-Right Lane

open access: yesJournal of Teaching and Learning with Technology, 2021
: This essay focuses on the role of humanities faculty in the modern university and the impact of technology on that role.
Ruth Savidge Turpin
doaj  

The Far Right Honeytrap: Georgian Media and the Mediagenic Far Right

open access: yes, 2020
The recent wave of far-right mobilization across the globe, including Georgia, naturally attracts wide media attention. Although the interrelation of the media and the far right, especially in the Georgian context, remains under-researched, evidence from other countries shows the potential impact of media coverage on both public opinion, i.e.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Ireland and immigration: explaining the absence of the far right [PDF]

open access: yes, 2007
Garner seeks to explain the absence of far-right political formations in the history of the Republic of Ireland, especially in relation to immigration.
Garner, Steve J., Garner, Steve
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

White youth: the Far Right, Punk and British youth culture [PDF]

open access: yes, 2016
‘White Youth’ recovers and explains the relationship between far-right organisations and British youth culture in the period between 1977 and 1987. In particular, it concentrates on the cultural spaces opened up by punk and the attempts made by the ...
Worley, Matthew   +2 more
core   +1 more source

“Je suis … Charlie, Samuel, Muhammed”: Practicing Muhammed Cartoons in Far Right and Islamist Politics

open access: yes, 2022
Since the 2005 Jyllands-Posten controversy, both far right and Islamist actors have employed Muhammed cartoons to construct a radical frontier between Muslims and non-Muslims.
de Groot Heupner, Susan
core   +1 more source

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