Results 71 to 80 of about 9,704,193 (294)

A Novel Modified Symmetric Nested Array for Mixed Far-Field and Near-Field Source Localization

open access: yesRemote Sensing
In the process of locating mixed far-field and near-field sources, sparse nonlinear arrays (SNAs) can achieve larger array apertures and higher degrees of freedom compared to traditional uniform linear arrays (ULAs) with the same number of sensors.
Zheng Xiang   +5 more
doaj   +1 more source

Far-field sound radiation due to an installed open rotor

open access: yes, 2012
Future single rotation propeller and contra-rotating advanced open rotor concepts promise a significant fuel efficiency advantage over current generation turbofan engines.
Kingan, Michael J., McAlpine, A.
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Helicity-delinked manipulations on surface waves and propagating waves by metasurfaces

open access: yesNanophotonics, 2020
Although many approaches have been proposed to manipulate propagating waves (PWs) and surface waves (SWs), usually each operation needs a separate meta-device, being unfavorable for optical integrations.
Li Shiqing   +9 more
doaj   +1 more source

Comparison of image reconstruction by using near-field and far-field data for an imperfect conductor

open access: yes, 2010
Image reconstruction by using near-field and far-field data for an imperfectly conducting cylinder is investigated. A conducting cylinder of unknown shape and conductivity scatters the incident wave in free space and the scattered near and far fields are
丘建青; Chiu, Chien-ching; Chen, Wei-ting
core   +1 more source

Narrow lateral far field divergence obtained with spatially modulated broad-area lasers

open access: yes, 2021
A laser design combining longitudinal-lateral gain-loss modulation with additional phase tailoring is presented. Under pulsed operation simulations predict a single-lobed far field angle of Θ40% = 0.4° at 100 A and far-field measurements confirm a ...
Zeghuzi, Anissa   +11 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Detection of recombinant proteins of Ha-FAR-1, Ha-FAR-2 and Hf-FAR-1 via SDS-PAGE

open access: yes, 2016
M: Protein marker; 1, 3, 5: Supernatant of unpurified Hf-FAR-1, Ha-FAR-1, Ha-FAR-2 respectively; 2, 4, 6: Purified Hf-FAR-1, Ha-FAR-1, Ha-FAR-2 respectively.
Xin Li (51274)   +10 more
core   +1 more source

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