Results 41 to 50 of about 5,126,039 (283)
Neither demarcation nor confrontation
Zeitschrift für Weiterbildungsforschung - Report, 2020 Right-wing populism has strongly polarizing effects in politics, education and science—a problem which this article aims to adress. Instead of claiming a demarcation between science and education on the one hand and right-wing populist ideology on the ...
Christoph Haker, Lukas Otterspeer
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The Emotional Dimension of the Spanish Far Right and Its Effects on Satisfaction with Democracy
Social Sciences, 2022 The recent rise of the far right in Spain highlights the importance of analysing the elements that have contributed to VOX’s success and the party’s ascent to the third political power in the country after the general election held in November 2019.
Erika Jaráiz Gulías +2 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The (far-) right kind of feeling
JournalisticaThe growth of far-right alternative news media and its influence on political debate highlights the need to understand the role of emotions in this type of media.
Magnus Danielson
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
When The Far-Right Reads Lacan
Studia Universitatis Babeș-Bolyai. PhilosophiaThis article examines the recent appropriation of Lacanian Psychoanalysis by Aleksandr Dugin, who utilizes Lacan as a resource for nationalist and illiberal politics.
Octavian-Ionuț OJOG
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source