Results 61 to 70 of about 5,930,841 (345)

Grand unification in the minimal left-right symmetric extension of the standard model

open access: yes, 2012
The simplest minimal left-right symmetric extension of the standard model is studied in the high energy limit, and some consequences of the grand unification hypothesis are explored assuming that the parity breaking scale is the only relevant energy ...
A Melfo   +22 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Pillars for Progress on the Right to Health: Harnessing the Potential of Human Rights Through a Framework Convention on Global Health [PDF]

open access: yes, 2012
Ever more constitutions incorporate the right to health, courts continue to expand their right to health jurisprudence, and communities and civil society increasingly turn to the right to health in their advocacy.
Friedman, Eric A., Gostin, Lawrence O.
core   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

KEBANGKITAN POLITIK KANAN-JAUH DAN DAMPAKNYA BAGI MULTIKULTURALISME DI EROPA1

open access: yesDauliyah, 2017
Since 1970s the far right movement began to reappear in Europe. The emergence of the movement became an interesting phenomenon in Europe. This is because the history of the movement that affiliated with facism that leads to World War II.
Rizky Hikmawan
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Populist Radical Right: Illiberal Erosion or Liberal Decay? Assessing Theoretical Explanations in the Wake of the 2024 European Parliament Election

open access: yesSocieties
This article identifies the structural factors underlying the rise of the Populist Radical Right (PRR) in Europe and evaluates its implications for liberal democracies. Our research finds that the emergence of the PRR is driven by the decay of democratic
Alfonso A. López-Rodríguez   +1 more
doaj   +1 more source

'POWs and purge victims: attitudes towards party rehabilitation, 1956-57' [PDF]

open access: yes, 2008
In the wake of Stalin's death in 1953 and Khrushchev's Secret Speech three years later, many Soviet citizens hoped that past injustices would now be put right. For some, this meant the right to rejoin the Communist Party. This article explores how former
Dobson, M.
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

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