Results 51 to 60 of about 5,919,115 (300)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The Critical Risk of Disinformation for Humanitarians – The Case of the MV Aquarius
Journal of Humanitarian Affairs, 2021 The search and rescue of refugees, asylum seekers and migrants on the Mediterranean has become a site of major political contestation in Europe, on the seas, in parliaments and government offices and in online public opinion.
Sean Healy, Victoria Russell
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A Short Historical Sociology of the Radical Right [PDF]
Codrul CosminuluiRichard Saull’s work on the far right makes a fundamental contribution to our knowledge of the post-fascist phenomenon in today’s world. Although the book presents itself as a historical sociology of the far-right’s connections with neoliberal ideology ...
Vlad Gafita
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Probing minimal supergravity in the type-I seesaw mechanism with lepton flavour violation at the CERN LHC [PDF]
, 2008 The most general supersymmetric seesaw mechanism has too many parameters to be predictive and thus can not be excluded by any measurements of lepton flavour violating (LFV) processes.
A. Villanova del Moral +7 more
core +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Fruit of a Vile Tree: The Eshelman Family\u27s War [PDF]
, 2015 Frederick Eshelman\u27s father wasn\u27t home. He was in Petersburg, the chilly and treacherous trenches stretching to his right and left as far as the imagination might take them. That\u27s where the danger was.
Rudy, John M.
core +1 more source