Results 51 to 60 of about 125,025 (153)

Bisphenols and Phthalates in Bottled Mineral Water: First Evidence of Co‐Occurrence, Estrogenic Activity, and Health Risk in Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), its structural analogs, and phthalates are synthetic chemicals widely used, with documented endocrine‐disrupting activity. This study aimed to develop and validate a selective multiresidue analytical method for the simultaneous determination of BPA, 10 bisphenol analogs, and six phthalates in PET‐bottled mineral water.
Giulia Boito Reyes, Lucas Correia Gonçalves, Fernanda Cristina Iba Molinari, José Eduardo Gonçalves   +3 more
wiley   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

LEVANTAMENTO DE NOTÍCIAS PUBLICADAS NA INTERNET SOBRE ROUBO DE CARGA DE MEDICAMENTOS NO BRASIL

Revista Contexto & Saúde, 2018
O objetivo deste estudo é coletar dados de notícias na Internet sobre roubo de carga de medicamentos no Brasil nos anos de 2014, 2015, 2016. Uma pesquisa transversal, documental e retrospectiva foi realizada no segundo semestre de 2016, utilizando a ...
Suelen Franco Pedrotti, Virgínia Petrini Maszlock, Tânia Alves Amador   +2 more
doaj   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

British Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva, Lidia Puertas‐Umbert, Judith Alonso, Rafael Almendra‐Pegueros, Saray Varona, Mercedes Camacho, Gemma Arderiu, Lluís Asmarats, Marta Alegret, Jose Martinez‐Gonzalez, Cristina Rodriguez   +10 more
wiley   +1 more source

Obstipação: caracterização do atendimento prestado por profissionais de farmácia em farmácias comunitárias do distrito de Lisboa [PDF]

, 2006
A obstipação aguda simples caracteriza-se como sendo uma situação clínica de duração não superior a três a cinco dias, em que o indivíduo apresenta algum desconforto abdominal, mas não manifesta nenhum outro sintoma mais grave.
Coelho, André, Costa, Ana Margarida, Massas, C., Motas, T., Sereno, B.   +4 more
core  

Peri‐Implant Crevicular Fluid Analysis by Mid‐Infrared Spectroscopy in Peri‐Implantitis—A Pilot Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study aimed to assess biochemical differences in peri‐implant crevicular fluid (PICF) using ATR‐FTIR spectroscopy and multivariate analysis, through a between‐participant comparison of healthy and peri‐implantitis (PI) sites, and a within‐participant comparison of PI‐PICF and GCF from contralateral periodontal healthy teeth ...
Francisco Maligno, Ricardo N. M. J. Páscoa, Pedro S. Gomes   +2 more
wiley   +1 more source

Proceedings from 9th Pharmacy Academic Conference [PDF]

, 2013
Livro de Atas do “IX Colóquio de Farmácia”: “Envelhecimento e Saúde” da “9 th Pharmacy Academic Conference Proceedings” em Abril de ...
Correia, Patrícia Carla dos Santos, Cruz, Agostinho, Cunha, Agostinho, Ferraz Oliveira, Rita, Jesus, Ângelo, Oliveira, Ana Isabel, Pinho, Cláudia, Santos, Marlene   +7 more
core  

Drought‐Induced Abscisic Acid Accumulation in Soybean Roots Depends on NCED Gene Expression More Than Shoot‐to‐Root ABA Transport

Plant, Cell &Environment, EarlyView.
Abstract Abscisic acid (ABA) is a key phytohormone in plant responses to water deficit. Although there is extensive evidence that roots can synthesise ABA, recent findings suggest that local synthesis in response to dehydration contributes little to the root ABA pool compared to shoot‐sourced ABA.
Jaime Puértolas, Pedro Castro‐Valdecantos, Moxian Chen, Jianhua Zhang, Ian C. Dodd   +4 more
wiley   +1 more source

Química e farmácia [PDF]

, 2015
A Europa pós-iluminista empenhou-se na afirmação da função e do estatuto da ciência e do impacto desta na sociedade, o que - a partir da terceira década do século XIX - uma conceção positivista do mundo (Auguste Comte, Herbert Spencer,…) só veio reforçar.
André, João P.
core  

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

The Journal of Physiology, EarlyView.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate, Carmen M. Vázquez   +6 more
wiley   +1 more source