CYP2C:TG Haplotype in Native Mexicans, Molecular Ancestry and Its Implications for CYP2C19 Genotype–Phenotype Correlation [PDF]
PharmaceuticalsBackground: Recent studies have associated the presence of the CYP2C:TG haplotype with increased metabolism of CYP2C19 substrates such as escitalopram and sertraline, suggesting a potential regulatory interaction between CYP2C18 and CYP2C19.
Carla González de la Cruz +9 more
doaj +2 more sources
Effects of IGF1 rs6214 Polymorphism and Milk Consumption on Serum Levels of IGF-1 and GH and Body Composition [PDF]
MetabolitesMilk and dairy are rich in insulin-like growth factor 1 (IGF-1), a protein secreted through the action of growth hormone (GH) and implicated in growth and metabolism.
Julio Cesar Grijalva-Avila +9 more
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PTPN9 regulates HER3 phosphorylation during trastuzumab treatment and loss of PTPN9 is a potential biomarker for trastuzumab resistance in HER2 positive breast cancer. [PDF]
Cancer Commun (Lond)Cancer Communications, Volume 45, Issue 1, Page 68-73, January 2025.
Azad A +15 more
europepmc +2 more sources
Selección de variantes farmacogenómicas y metodología para su uso en farmacia comunitaria [PDF]
Farmacéuticos ComunitariosLos organismos reguladores, como la Food and Drug Administration (FDA) y la European Medicines Agency (EMA), reconocen la farmacogenética como una herramienta clave en sus guías farmacológicas para el asesoramiento farmacéutico.
Almudena Montero-Gómez +1 more
doaj +2 more sources
Rapid Identification of Drug Resistance and Phylogeny in M. tuberculosis, Directly from Sputum Samples [PDF]
Microbiology Spectrum, 2022 Tuberculosis (TB) remains one of the most important infectious diseases globally. Establishing a resistance profile from the initial TB diagnosis is a priority.
Martín Barbosa-Amezcua +10 more
doaj +2 more sources
Farmacogenômica e Doença Cardiovascular: Onde Estamos e Para Onde Vamos [PDF]
Arquivos Brasileiros de Cardiologia, 2020 Resumo A farmacogenômica (FGx) investiga a interação entre genes e medicamentos. Através da análise de regiões específicas do DNA, informações sobre o perfil de metabolização do paciente para um determinado fármaco podem ser descritas, assim como o ...
Ricardo Stein +3 more
doaj +4 more sources
The Microbiome as Part of the Contemporary View of Tuberculosis Disease [PDF]
Pathogens, 2022 The study of the microbiome has changed our overall perspective on health and disease. Although studies of the lung microbiome have lagged behind those on the gastrointestinal microbiome, there is now evidence that the lung microbiome is a rich, dynamic ...
Martín Barbosa-Amezcua +3 more
doaj +2 more sources
Plasma Hepcidin as a potential informative biomarker of Alzheimer disease and vascular dementia [PDF]
Alzheimer’s Research & TherapyBackground Blood-based assays are expected to be integrated into clinical routines across various contexts, including Alzheimer’s disease (AD). Vascular dementia (VaD), which is the second most common cause leading to dementia after AD, could also ...
Constance Delaby +16 more
doaj +2 more sources
Farmacogenética y medicina de laboratorio: del gen individual a los estudios genéticos integrales [PDF]
Advances in Laboratory MedicineSerra Mercè Brunet +1 more
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Otimização da terapia medicamentosa através de testes farmacogênomicos
Jornal de Assistência Farmacêutica e Farmacoeconomia, 2023 Introdução: A farmacogenômica é uma associação do conhecimento da farmacologia clássica e ciência genômica para a medicina personalizada e o uso racional de medicamentos.
Ravena Santos Costa +6 more
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