Results 21 to 30 of about 9,044 (171)
Journal of Applied Toxicology, EarlyView.ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado +9 more
wiley +1 more source
Lipids, EarlyView.The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr +5 more
wiley +1 more source
Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models
Environmental Toxicology, EarlyView.ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa +9 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT The association between pesticide exposure and Parkinson's disease (PD) is substantial, but heterogeneity in methodology and lack of categorization according to the type of exposure and pesticide classes in previous meta‐analyses impair the interpretation of data. This study aims to update evidence of the association between pesticide exposure
Pedro Henrique Passos da Silva +6 more
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2016 In Brazil, scientific performance of researchers is one important criteria for decision-making in grant allocation. In this context, this study aimed to evaluate and compare the profile of 82 seniors' investigators (graded as level 1A-D) which were ...
JEAN P. KAMDEM +6 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues +8 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle +12 more
wiley +1 more source
Entrevista con la Dra. Ivonne Torres
Prisma Tecnológico, 2017 Polifacética, amistosa y conciliadora: así se describe la doctora en Farmacología Ivonne Torres Atencio. Su trayectoria profesional y personal la han llevado desde Puerto Armuelles, provincia de Chiriquí, tierra que la vio nacer, hasta Barcelona, la ...
Astrid Scheuermann
doaj
Journal of Fish Biology, EarlyView.Abstract This study evaluated the physiological, metabolic and oxidative responses of Colossoma macropomum subjected to air exposure when maintained in water at suboptimal temperature (23°C). A total of 54 fish (81.33 ± 11.90 g) were distributed into nine tanks (6 fish per tank). For the air exposure test, 24 animals were exposed for 30 min and another
Gisele Cristina Favero +8 more
wiley +1 more source