Results 41 to 50 of about 9,044 (171)

Problemas que limitan la interdisciplinariedad entre la Farmacología y las asignaturas clínicas en Estomatología

Gaceta Médica Espirituana, 2021
Fundamento: El desarrollo de la interdisciplinariedad entre la unidad curricular Farmacología y las asignaturas clínicas de la Disciplina Principal Integradora en la carrera Estomatología, resulta indispensable para la formación integral del futuro ...
Ana Ibis Bosch Nuñez, Oscar Rodríguez Reyes   +1 more
doaj  

Farmacologia do fibratos [PDF]

Arquivos Brasileiros de Cardiologia, 2005
Os fibratos são as drogas de escolha nas hipertrigliceridemias. Após sua absorção, os fibratos são metabolizados pelo fígado, utilizando isoenzimas P450 não compartilhadas pelas estatinas. Entretanto, para alguns fibratos, como o genfibrozil, uma interação com estatinas pode ocorrer durante a sua glucuronidação, ou pelo deslocamento de frações livres ...
openaire   +3 more sources

HLA‐B*44 Alleles and HLA‐DQA1*03:01 as Genetic Risk Factors for Drug‐Induced Liver Injury due to Fluoroquinolones

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Fluoroquinolone exposure can give rise to drug‐induced liver injury. Genetic risk factors for this form of liver injury are poorly understood but some evidence suggests that HLA genes contribute. This study aimed to characterise HLA risk factors for fluoroquinolone‐induced liver injury in a European population. Methods From
Paola Nicoletti, M. Isabel Lucena, Raul J. Andrade, Samreen Zafer, Einar S. Bjornsson, Pär Hallberg, Dominique Larrey, Mariam Molokhia, Mia Wadelius, Guruprasad P. Aithal, Ann K. Daly   +10 more
wiley   +1 more source

Emulsão e microemulsão: novos sistemas de liberação controlada

Medicina Veterinária, 2017
  A utilização de forma indiscriminada dos medicamentos veterinários não compromete apenas a eficiência, mas também elevam os custos dos tratamentos, independente da espécie animal.
SRL Basto, JC Ferreira-Silva, FLA Silva, GAS Aleixo, TCM Stamford, MV Silva, MTS Correia   +6 more
doaj  

Pituitary Neurolobectomy induces sustained hypotension in male Wistar rats and normalizes blood pressure in male spontaneously hypertensive rats

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Arginine vasopressin is primarily recognized as an osmoregulatory hormone; however, its contribution to vascular tone and blood pressure regulation under basal and hypertensive conditions remains debated. This study examined the effects of vasopressin deficiency induced by neurointermediate pituitary lobectomy in Wistar and spontaneously ...
Gloria Marcela Villanueva‐Rodríguez, Norma A. Bobadilla, J. Luis Quintanar, Claudia Verónica Rivera‐Cerecedo, David Roberto Chavira‐Ramírez, Kalman Kovacs, Andrés Quintanar‐Stephano   +6 more
wiley   +1 more source

Design, Synthesis, and Evaluation of Coumarin‐Rasagiline Hybrids as Multifunctional Neuroprotective Agents

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
Novel coumarin‐rasagiline hybrid molecules were designed and synthesized as multifunctional agents targeting key pathological mechanisms of neurodegenerative diseases. These compounds exhibited hMAO‐B inhibitory activity, antioxidant and neuroprotective effects, supported by ADMET profiling and molecular modeling studies. The design of hybrid molecules
Aitor Carneiro, Sandra Barreiro, Claudia Sofia Machado, Miguel Pinto, Daniel Chavarria, Manuel Novás, Davide Crucitti, Carlos Fernandes, Maria João Matos   +8 more
wiley   +1 more source

Utilização de passiflora incarnata no tratamento da ansiedade

UNINGÁ Review, 2017
Os medicamentos fitoterápicos obtidos através de matérias primas ativas vegetais foram regulamentados no Brasil como medicamentos convencionais, apresentando critérios similares de qualidade, segurança e eficácia requeridos pela ANVISA para
MAYKE WILLIAN LOPES, ROGERIO TIYO, VINICIUS PEREIRA ARANTES   +2 more
doaj  

Hair Cortisol Concentrations in Children: A Longitudinal Analysis Across Childhood

Developmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Hair cortisol concentration (HCC) reflects long‐term cortisol exposure and is commonly used as a biomarker of hypothalamic–pituitary–adrenal axis activity. Although increasingly applied in pediatric populations, developmental changes in HCC and potential sex differences remain unclear.
Miguel Ángel Baos‐González, Javier De Echarri‐Lorente, María Ángeles García‐León, Raquel González‐Pérez, María Isabel Peralta‐Ramírez   +4 more
wiley   +1 more source

Hipertensão arterial sistêmica: aspectos clínicos e análise farmacológica no tratamento dos pacientes de um setor de psicogeriatria do Instituto Bairral de Psiquiatria, no município de Itapira, SP

Revista Brasileira de Geriatria e Gerontologia
OBJETIVO: o presente trabalho teve como objetivo a verificação dos quadros de hipertensão arterial sistêmica (HAS) e análise das principais classes dos agentes anti-hipertensivos orais usados pelos pacientes integrantes da Unidade Terapêutica - Setor ...
Marco Aurelio Tosta Longo, Anderson Martelli, Anita Zimmermann   +2 more
doaj   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source