Results 41 to 50 of about 45,914 (215)

Entrevista con la Dra. Ivonne Torres

Prisma Tecnológico, 2017
Polifacética, amistosa y conciliadora: así se describe la doctora en Farmacología Ivonne Torres Atencio. Su trayectoria profesional y personal la han llevado desde Puerto Armuelles, provincia de Chiriquí, tierra que la vio nacer, hasta Barcelona, la ...
Astrid Scheuermann
doaj  

Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder

Addiction Biology, Volume 31, Issue 5, May 2026.
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino, Raissa Mazzer de Sino Romano, Regiane Chiavelli Lamim, Rafael Conte, Denise Ribeiro Gobbo, Marcelo Carvalho da Conceição, Vanessa Kiyomi Ota, Lucas Liro, Leslie Domenici Kulikowsk, Adriana Marcassa Tucci, Ana Lucia de Moraes Horta, Ana Maria Sebastião, Maria Lucia Oliveira Souza‐Formigoni, João Ricardo Nickenig Vissoci, Alexandre Ferro Aissa, Isabel Cristina Céspedes   +15 more
wiley   +1 more source

Farmacologia Antiviral

, 2021
Fil: Eddi, Carlos S..
Errecalde, Jorge Oscar, Marin, Gustavo Horacio, Eddi, Carlos S.   +2 more
openaire   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, Volume 183, Issue 10, Page 2177-2196, May 2026.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Possibilidades terapêuticas e risco toxicológico de Jatropha gossypiifolia L.: uma revisão narrativa Therapeutic possibilities and toxicological risk of Jatropha gossypiifolia L.: a narrative review

Revista Brasileira de Plantas Medicinais, 2010
A espécie Jatropha gossypiifolia L. (Euphorbiaceae), popularmente conhecida como pião-roxo, entre tantos outros nomes, é um bom exemplo do tênue limiar que separa o efeito terapêutico do tóxico.
S.R. Mariz, A.C.R. Borges, M.F.F. Melo-Diniz, I.A. Medeiros   +3 more
doaj   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, Volume 183, Issue 10, Page 2256-2272, May 2026.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Sintesi di nuovi sistemi triciclici aromatici lineari. Triazolochinoloni, imidazochinoloni e 4-osso-piridochinossaline quali potenziali agenti DNA intercalanti [PDF]

, 2002
Recentemente abbiamo riportato la sintesi di alcuni nuovi sistemi triciclici lineari aromatici azotati che per la loro tipicità, una volta opportunamente funzionalizzati, potranno essere saggiati al fine di valutarne la potenzialità ...
Carta, Antonio, Falchetto, Manuela, Sanna, Paolo Antonio   +2 more
core  

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]

, 2018
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik, Enemark, Heidi L., López-Muñoz, Rodrigo, Peña-Espinoza, Miguel, Simonsen, Henrik T., Thamsborg, Stig M., Valente, Angela H., Williams, Andrew R.   +7 more
core   +4 more sources

Farmacodermia em cão da raça Dálmata: Relato de caso

Pubvet, 2018
Entende-se como farmacodermia a reação de hipersensibilidade a determinados fármacos manifestada por lesões dermatológicas focais ou difusas. Este trabalho apresenta um caso de farmacodermia em cão após administração de amoxicilina associada a ...
Claudio Douglas de Oliveira Guimarães, Caio Vitor Cavalcante de Carvalho, Ene Madeira de Oliveira Aires, Mário José Costa Carneiro, Maridelzira Betânia Moraes David, Luiz Fernando Moraes Moreira   +5 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Triazine‐Based Dual Histone Deacetylase/phosphatidylinositol 3‐kinase Inhibitors for Breast Cancer Therapy

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Breast cancer is the most frequently diagnosed malignancy and a leading cause of cancer‐related mortality among women worldwide. Triple‐negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive nature, limited therapeutic options, and high propensity for drug resistance.
Lara Luzietti, Gustavo Salgado Pires, Ana Ryan, Crisamie Regidor, Matthew Hiller, Danilo Sarti, Tríona Ní Chonghaile, Pedro de Sena Murteira Pinheiro, Damir Varešlija, Daniel Alencar Rodrigues   +9 more
wiley   +1 more source