Results 31 to 40 of about 45,579 (198)

A Reproducible Workflow for Macrophage Membrane Isolation and Nanocore Selection Toward Bioinspired Nanoparticles Targeting Immunologically Cold Tumors

open access: yesSmall Methods, EarlyView.
A reproducible workflow is established for isolating macrophage membranes to enable the efficient preparation and characterization of membrane‐coated nanoparticles. By optimizing M2‐like nanovesicle stability and nanocore compatibility, this procedure advances the engineering of macrophage membrane‐coated nanoparticles with improved tumor targeting ...
Diana Peixoto   +6 more
wiley   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa   +9 more
wiley   +1 more source

O ENSINO DE FARMACOLOGIA MÉDICA DIRECIONADO À REALIDADE: EXEMPLO DE UMA EXPERIÊNCIA PIONEIRA [PDF]

open access: yesRevista Brasileira de Educação Médica, 2020
Resumo Os autores preconizam o ensino de Farmacologia Médica voltado à realidade de prescrição em nosso meio, relatando experiências pedagógicas fundamentadas na solução de problemas.
Flávio Danni Fuchs   +2 more
doaj   +1 more source

Prendre antiagregants augmenta el risc de patir una hemorràgia digestiva [PDF]

open access: yes, 2006
Fins ara es coneixia que els fàrmacs antiagregants, malgrat els seus beneficis per prevenir malalties cardiovasculars, podien resultar perjudicials per l'aparell digestiu.
Ibáñez, Luisa
core   +1 more source

José Ribeiro do Valle e a endocrinologia paulista [PDF]

open access: yes, 2001
Universidade Federal de São Paulo (UNIFESP) Disciplina de EndocrinologiaUNIFESP, Disciplina de ...
Verreschi, Ieda Therezinha do Nascimento
core   +1 more source

Revisiting the Association of Pesticide Exposure and Parkinson's Disease: Systematic Review and Meta‐Analysis

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The association between pesticide exposure and Parkinson's disease (PD) is substantial, but heterogeneity in methodology and lack of categorization according to the type of exposure and pesticide classes in previous meta‐analyses impair the interpretation of data. This study aims to update evidence of the association between pesticide exposure
Pedro Henrique Passos da Silva   +6 more
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

open access: yesBritish Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi   +10 more
wiley   +1 more source

Scientific Performance of Brazilian Researchers in Pharmacology with grants from CNPq: A comparative study within the Brazilian categories

open access: yesAnais da Academia Brasileira de Ciências, 2016
In Brazil, scientific performance of researchers is one important criteria for decision-making in grant allocation. In this context, this study aimed to evaluate and compare the profile of 82 seniors' investigators (graded as level 1A-D) which were ...
JEAN P. KAMDEM   +6 more
doaj   +1 more source

Farmacologia no século XX: a ciência dos medicamentos a partir da análise do livro de Goodman e Gilman [PDF]

open access: yesHistória, Ciências, Saúde: Manguinhos, 2013
Analisa a apresentação da farmacologia como ciência a partir do livro-texto de Louis Goodman e Alfred Gilman reeditado e reimpresso inúmeras vezes entre 1941 e 2006.
Silvia Cardoso Bittencourt   +2 more
doaj   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado   +6 more
wiley   +1 more source

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