Results 21 to 30 of about 180,185 (219)

Pregnant Women's Knowledge And Attitudes About High-Risk Pregnancy: The Effect of Using the JIPH Educational Application

open access: yesPublic Health of Indonesia
Background:Early detection and screening of risk factors among pregnant women are essential efforts to identify potential risks during pregnancy. The impacts of these risks may include miscarriage, obstructed labor, antepartum hemorrhage, stillbirth ...
Farming Nawir   +3 more
doaj   +1 more source

INSTITUTIONAL APPROACHES OF MODERN SOCIO-ECOLOGO-ECONOMIC FORMS OF ECONOMY IN AGRARIAN SECTOR OF ECONOMY OF UKRAINE

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2014
Main problems of agrarian sector of economy of Ukraine are revealed. Main directions of development of agriculture of Ukraine are determined. The necessity of socio-ecologo-economic agrarian sector is proved.
O. Pimenova
doaj   +1 more source

Misalignment of perceptions with records and resources for responding to climate change risk

open access: yesFrontiers in Climate, 2022
Climate change risks like extreme temperatures and high variability in rainfall adversely affect livelihoods, particularly for farmers in Burkina Faso where the primary sector is agriculture.
Sudha Kannan   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Empowering Indigenous Farmers with Fish Farming on South Sumatra Peatlands

open access: yesHabitat, 2021
Forest and land fire is mentioned as a main problem of peatlands occurring every year and has provided huge losses for all parties. The research aimed how to empower indigenous farmers with fish farming on South Sumatra peatlands.
Elisa Wildayana, M. Edy Armanto
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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